GI prophylaxis

GI prophylaxis used under the following conditions:

  • Elderly, age >60

  • Shock

  • Severe sepsis

  • >30% burn

  • Multiple organ failure

  • Coagulopathy

  • Prior GI event

  • High NSAID dose

  • Anticoagulation

  • Head trauma

  • Quadriplegia

  • Steroid use

  • Mechanical vent >48 hr

    • GIB - Protonix IV 80 mg IV bolus, followed by 8 mg/h IV x 12 h