T - Cell disorders
Immunodeficiency, may be primary or secondary.
It may involve primarily B cells or subsets of T cells, or it may be generalized and involve the entire immune system.
All immunodeficiencies are characterized by lymphopenia, a low lymphocyte count in the peripheral blood.
B-cell deficiencies are associated with low levels of serum immunoglobulins.
Defective or inadequate function of T cells may be detected by immunologic tests for CMI (e.g., a patch test or tuberculin test).
B-Cell disorders
B and T cell disorders
H&P, CBC, Sr. Ig levels
T-cell fx: anergy panel skin test (PPD, candidia, histoplasmin, tetanus toxoid)
T-cell assays: CD4, CD8, CD3, T-cell receptor.
B-cell assays: CD19, CD20, CD21, Ig associated.
Phagocyte dysfunction