Hereditary immunodeficieny states

• Immunodeficiency, may be primary or secondary.

• It may involve primarily B cells or subsets of T cells, or it may be generalized and involve the entire immune system.

• All immunodeficiencies are characterized by lymphopenia, a low lymphocyte count in the peripheral blood.

  • B-cell deficiencies are associated with low levels of serum immunoglobulins.

  • Defective or inadequate function of T cells may be detected by immunologic tests for CMI (e.g., a patch test or tuberculin test).

B-Cell disorders

Phagocyte dysfunction