Rash
First, make sure this is not an anaphylactic reaction.
Look for urticarial rash with associated SOB, wheezing, laryngeal edema, and hypotension.
If these Sx are present, consider the following:
Large bore (16 gauge) access for IVF
Epinephrine, 0.5 mg (1:1000) SQ or IV (dilute in 10 mL saline.
Benardryl, 50 mg IV or 50 - 100 mg IM
Hydrocortisone, 250 mg IV
Intubation if airway is compromised
The most common cause of rashes inpatient is a drug reaction, so review medication list (MAR)
Hold any medication that may be the cause if this is not an essential medicaiton
Benadryl, 25 - 50 mg PO q6 - 8 hr PM; Atarax, 25 mg PO q6 - 8 hr PM; Allegra, 180 mg PO daily; or Claritin, 10 mg PO daily, if itching is present.
Corticosteroid creams or PO steroids, if severe.
Consider dermatology consult or allergy consult (for desensitization) in AM.