Lupus - drug induced

Lupus-drug induced (DIL)

• • Drugs causing:

    • Isoniazid

    • Procainamide

    • Hydralazine

    • Quinidine

    • Methyldopa

    • Chlorpromazine

    • D-Penicillamine

    • Alpha-interferon

  • Cause sx similar to SLE,such as arthralgia, fever, and serositis. Renal and CNS manifestations are rare, however.

  • Disease remits by removal of drug.

  • Anti-histone-ab positive.