Lupus - drug induced

Lupus-drug induced (DIL)

    • Drugs causing:

      • Isoniazid

      • Procainamide

      • Hydralazine

      • Quinidine

      • Methyldopa

      • Chlorpromazine

      • D-Penicillamine

      • Alpha-interferon

    • Cause sx similar to SLE,such as arthralgia, fever, and serositis. Renal and CNS manifestations are rare, however.

    • Disease remits by removal of drug.

    • Anti-histone-ab positive.