Frost is the term that refers to a class of drugs, purportedly developed by Dr. Dubious. Its name comes from two aspects, both its white powdery appearance like that of snow, as well as a common side-effect of getting the chills.
It is derived from a consequential byproduct of the F. solaris bacteria that enables it to survive at near freezing conditions.
It has some addictive properties, and there are some people who heavily depend on it. They are frequently referred to as "Frostitutes." They'll do anything to get their fix. Frostitution is particularly prevalent in areas of high population density, such as The Can.