Please write a summary of the group comments (1 paragraph) regarding your presentation. This summary should be posted here as soon as possible after the meeting. Most importantly the summary should include key points that you need to address or resolve. I will review your summary at the next meeting and you should be prepared to discuss your progress on these issues.
Meeting Date: Jan. 6, 2009
Summary (DONE):
1. Manuscript Revision (Masoud’s paper): writing an initial revision draft
2. Manuscript Revision and Submission (Dr. Seunghwan Lee’s manuscript): ~Dec. 28
3. Manuscript Internal Revision (Dr. Jaehong Park’s manuscript): ~ Dec. 28
4. Book Chapter (microfluidics): draft/sent to Adam and Nezam
5. Grant Supplemental Report (R01 – NIBIB Supplemental): editing
6. Microfluidics experiments (visualization with Dr. Sim): ~ Dec. 22
7. Design of experiment (for Giuseppina’s project): proof-of-concept for cancer cell microfluidics (reported to Ali)
8. Design of experiment (for Onur and Shilpa’s project): metal mask (completed) communicated by Dr. Ahn@NanoFab Center (he required a summary of this project’s aim)
9. Design of experiment (for Shilpa’s project): initial design of nanopattern and its feasibility check plan (reported to Ali)
Future Plan (TODO):
1. Grant Supplemental Report (R01 – NIBIB Supplemental): revision with Ali for submission
2. Book Chapter (microfluidics): revision with Ali for submission after Adam’s work
3. Microfluidics experiments (mixing and cell docking with Dr. Sim): continued
4. Paper Preparation (PDMS electrification): writing the results in a paper format
5. PDMS hollow sphere paper II (self-assembly): PDMS experiments (advanced, Won Gu), COMSOL simulations (Masoud), and theory (Matt).
6. Design of experiment (for Giuseppina’s project): ~continued
7. Fabrication (for Onur and Shilpa’s project): PEG microstructure fabrication
8. Design of experiment (for Shilpa’s project): Design of nanostructures (spherical, [hemispherical], cylindrical, and conical)
Progress on issues from last meeting:
Ali's comments:
Can you get the microfluidic system working for the stem cell project?
What is the validation experiment?
We need to move forward with the microfluidic?
Can we recruit people on it?
Won Gu's responses to Ali's comments:
Yes, I can. I will focus more on biological insights for this project by doing cell experiments.
In my experiments, the validation means a kind of scientific & technical evaluation of feasibility of this device for generating, controlling, and screening stem cell microenvironments. From now I will focus more on cell experiments.
Yes. When I first came to this lab, I devoted myself to this project with high motivation. As time goes by, however, I became tired with doing this project with low efficieny and difficulty in fabrication at that time. But now is different situation because I have some MEMS-professional persons that can help me to move forward this project, e.g., Dr. Sim. As Prof. JWHong mentioned before, multilayered chip fabrication is one of the most difficult sequence of this project, actually speaking, it might occupy more than half of this project for its success. In this point of view, I confirm we need to move forward this project. As I talked in the subgroup meeting, Dr. Sim and I will do mixing and cell experiments.
Sure. I'd love to. There is still very low throughput in chip fabrication even if Dr. Sim gave me his hands. To increase # of chip samples, I'd like to recruit more persons soon. (please see the below)
*NOTE: a brief report for a current throughput of chip fabrication (NOT including a period of fabrication protocol establishment)
Excellent (MTL fabrication level - for publication): nearly zero
Good (Lab fabrication - for visualization only): 1 per two weeks
Meeting Date: Jan. 27, 2009 10:00 am (Microfluidics) / 3:00 pm (Stem cells)
Summary (DONE):
1. Grant Supplemental Report (R01 – NIBIB Supplemental): DONE
2. Book Chapter (microfluidics): under revision of Ali DONE
3. Microfluidics experiments (cell docking with Dr. Sim): DONE, but require more experiments (cell culture in progress)
4. Fabrication of mold (for Onur and Shilpa’s project): DONE
5. Design of experiment (for Shilpa’s project): DONE, but I'm just waiting fro Dr. Ahn's response for feasibility of nanofabrication
6. Paper Revision & Correction (Integrative Biology): DONE
7. Recruiting person for microfluidics project in network: Behnamzamanian joined (to increase the # of the chip fabricated by multilayered softlithography and then decrease CV(coefficient of variation) of experimental results )
8. AHA Postdoctoral Fellowship Submission: Almost DONE (Now waiting for two reference reports and cosponsor packet)
Future Plan (TODO):
1. Grant Preparation (R01 – Cardiac Microfluidics, Specific Aim 1): my part has been sent to Instructor, Dr. Chung and is now under review.
2. Microfluidics experiments (mixing and cell docking with Dr. Sim): ~continued
3. Paper Preparation (PDMS electrification): writing a draft in a paper format (Dr. Moon: device setup and evaluation/ Dr. Kim: GC)
4. PDMS hollow sphere paper II (self-assembly): PDMS experiments (advanced, Won Gu), COMSOL simulations (Masoud), and theory (Matt).
5. Fabrication of microstructures (collaboration with Dr. Blaine Phiffer): PEG microstructure fabrication
6. Design of experiment (for Shilpa’s project): waiting for Dr. Ahn's response for feasibility of design of nanostructures (spherical, [hemispherical], cylindrical, and conical)
7. Recruiting person for microfluidics project out of network: UROP (for cell culture and biological sample preparation)
8. AHA Postdoctoral Fellowship Submission: Due date is January 27, 2009 (waiting for two reference reports and cosponsor packet)
Key progress on issues from last meeting (based on Ali's comments):
1. NIH R01 Late Breaking Supplemental Data Submission
2. NIH R01 New Submission Preparation
3. AHA Postdoctoral Fellowship Application Submission
4. Book Chapter Writing (In Ali's review)
5. RSC Integrative Biology (In press)
6. Microfluidics Projects (In progress)
Meeting Date:
Summary:
Action Plan:
Progress on issues from last meeting: