DATE CREATED:
Dec. 11th, 2008
ACTION PLAN
PROBLEMS IDENTIFIED (PI) / OUTSIDE SKILL REQUIRED (OSR) / RESOLVED (R)
PAPER TITLE
A) Background.
B) Specific Aims:
C) General Experimental Approach (Design etc):
D) Design Pitfalls and alternatives
E) Potential Figures:
F) Future Directions:
A) BACKGROUND:
microfabricated system for in vitro control of cell microenviroment and application for HTS
B) SPECIFIC AIMS
AIM 1 - reversible sealing PDMS microfluidic system for control interaction b/w cells and soluble materials.
AIM 2 - PEG
C) GENERAL EXPERIMENTAL APPROACH
PDMS sealing, PEG sealing. Hydrophobic, hydrophilic, covalent binding.
D) DESIGN PITFALLS AND ALTERNATIVES
E) POTENTIAL FIGURES FOR PAPER
scheme, cell life time, cell/materials pattern, materials release speed, cell-materials interaction
F) FUTURE DIRECTIONS
To expend materials sources: drug, growth factor, proteins.
To pattern two types of cells or more