5-14-09

May 14^th 2009 subgroup meeting

Javier: Introduce of outline about endotheliahlized tube and encapsulated inside the bulk collagen gel. The functional tube is used provide nutrient for the collagen gel and provide endothelial cells to induce the angiogenesis in the collagen material.

Suggestion:

· Define the scientific question to be answered;

· Polymer tube good for tissue engineering?

· Try to come out the simplest experimental setup to answer the questions

· Define the functionality.

· Clear demonstration of the concentration gradient of VEGF induced sprouting?

Masoud and Bonggeun:

· Design side groove with different degree of design of 90 and 30 degree of side channel

· Show that the experimental be reproducible by using histogram.

Suggestion:

· Do the confidence test of the histogram to represent better of the results;

· Do the 2D plot of the histogram;

Dr. Sim

· Achieve cell loading and test the viability of the stem cell in the well.

· Do the reference search on mechanical stimulation on the stem cell differentiation, found out the closest paper to his research.

· Having problem with evaluating the differentiation of the stem cell using RT-PCR due to the lack of cell number.

· Simplify the system to answer the question.

Suggestion:

· Try to define science that can give a paper

· Re-discuss the paper to make progress

Jiankang

Introduce the new outline about generating anisotropic composite materials

Suggestion:

· Change the title indicating scaffold formation and show the difference from the previous one

· Make the figures more specific

· Mention the details

· Mechanical testing of the materials

· Define specifically of assays used for the high-throughput screening

· Decouple for developing a tool or using it for engineering bone-cartilage interface