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王澤瑋 (Tse-Wei Wang)
王澤瑋 (Tse-Wei Wang)
The Feasibility Study of the Portable Intramuscular Injection Device and Its Design
The Feasibility Study of the Portable Intramuscular Injection Device and Its Design
可攜式肌肉注射裝置之可行性分析與設計
可攜式肌肉注射裝置之可行性分析與設計
Syringe injection is one of the conventional administration methods. In which, intramuscular injection is particular to some emergency medicines, for example, atropine. The needle-free injection improved many drawbacks and benefit to the EMT members in training and their usage.
Syringe injection is one of the conventional administration methods. In which, intramuscular injection is particular to some emergency medicines, for example, atropine. The needle-free injection improved many drawbacks and benefit to the EMT members in training and their usage.
The focus of this thesis is the design of a portable needle-free intramuscular injection device. According to pharmacology and nursing, the specification of the injection depth is set as 25 mm underneath the skin surface. Meanwhile, according to the fluid mechanics theory and the commercial product Medi-jector VISIONR, a model of the relation between piston pressure and outlet injection velocity is constructed and its accuracy is verified by measuring the outlet velocity and the output power of VISIONR. In respect of the difficulty of obtaining the human tissue, the test body of the anti-puncture property experiment is resorted to the porcine tissue. In order for investigating the anti-puncture property of the porcine tissue, the MTS Tytron 250 test machine is chosen to execute the experiment. Since the thickness of human skin and subcutaneous fat are lower than porcine tissue; and under the assumption that all the subcutaneous fat and muscle property of porcine are similar to human, including the penetration stress and the friction force during penetration. The human skin property, the porcine subcutaneous fat and muscle property are subjected to a human tissue geometry model for estimating the penetration stress of human body. Under the estimation, the penetration stress of human body is 71 MPa, which can be transformed into velocity form, 376.83 m/s, and the specification of the injection velocity is developed as 376.83 m/s.
The focus of this thesis is the design of a portable needle-free intramuscular injection device. According to pharmacology and nursing, the specification of the injection depth is set as 25 mm underneath the skin surface. Meanwhile, according to the fluid mechanics theory and the commercial product Medi-jector VISIONR, a model of the relation between piston pressure and outlet injection velocity is constructed and its accuracy is verified by measuring the outlet velocity and the output power of VISIONR. In respect of the difficulty of obtaining the human tissue, the test body of the anti-puncture property experiment is resorted to the porcine tissue. In order for investigating the anti-puncture property of the porcine tissue, the MTS Tytron 250 test machine is chosen to execute the experiment. Since the thickness of human skin and subcutaneous fat are lower than porcine tissue; and under the assumption that all the subcutaneous fat and muscle property of porcine are similar to human, including the penetration stress and the friction force during penetration. The human skin property, the porcine subcutaneous fat and muscle property are subjected to a human tissue geometry model for estimating the penetration stress of human body. Under the estimation, the penetration stress of human body is 71 MPa, which can be transformed into velocity form, 376.83 m/s, and the specification of the injection velocity is developed as 376.83 m/s.
Three modules of the portable needle-free intramuscular injection device are proposed after the specifications are developed: power unit module, cartridge and piston module and nozzle module. The pneumatic power source is chosen as the power unit module after the comparison of four types of the power. In which, the 12 gauge CO2 gas cylinder is chosen in the device. The nozzle from the commercial product VISIONR, which is 176 mm in nozzle diameter, is chosen as the nozzle of the device. For reaching the injection velocity of specification, 376.83 m/s, the area between the piston and the gas cylinder is set as 8.28 times of the piston. As the result, the 12 G gas cylinder can afford to push the stream in the specification velocity. The volume of cartridge is set as 3 ml in compliance with the ampoule of the conventional package of medicines. Eventually, the detail of the device is proposed and the design of the needle-free intramuscular injection device is finished.
Three modules of the portable needle-free intramuscular injection device are proposed after the specifications are developed: power unit module, cartridge and piston module and nozzle module. The pneumatic power source is chosen as the power unit module after the comparison of four types of the power. In which, the 12 gauge CO2 gas cylinder is chosen in the device. The nozzle from the commercial product VISIONR, which is 176 mm in nozzle diameter, is chosen as the nozzle of the device. For reaching the injection velocity of specification, 376.83 m/s, the area between the piston and the gas cylinder is set as 8.28 times of the piston. As the result, the 12 G gas cylinder can afford to push the stream in the specification velocity. The volume of cartridge is set as 3 ml in compliance with the ampoule of the conventional package of medicines. Eventually, the detail of the device is proposed and the design of the needle-free intramuscular injection device is finished.
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