Of six daughters and six sons born to Ludwig and Balbina (Mayer) Roth, Agatha was the 10th child. She was born on December 30, 1901, in Heudorf, Baden, Germany, on a small farm which was left to the care of her mother when her husband died at the age of 53. The older children went to work in order to support the family, while Balbina remained at home to care for the farm, home, and children.

One after another the children left home. Only the oldest girl married. One brother became a Franciscan brother, two sisters entered the Franciscans of the Holy Cross, one became a Good Shepherd sister, and two became Benedictine Sisters of Perpetual Adoration. Her Benedictine sister, Sr. M. Rosina Roth, died in 1995.

Agatha experienced a vocation to religious life from childhood. Already as a small child, she liked to ring the church bells. As their home was close to the parish church, she would run there to ring the Angelus. She rejoiced when, later in life, she was asked to take care of ringing the bells at Clyde.

In the years that followed World War I, there were many young women in Europe who did not have the necessary dowry to enter religious life there. Sr. M. Bernard Willmann, a competent and determined woman, made two Atlantic crossings to recruit postulants in Germany and Switzerland for the growing Clyde community. Equipped with letters of introduction, she went from place to place, and sent interesting accounts of her travels back to Clyde. On August 25, 1923, Sr. M. Bernard landed in New York, accompanied by twenty-three prospective postulants. Agatha Roth was among this first group.

As a postulant, Agatha worked in the garden, and later, as a novice, in the kitchen. When Mother M. Dolorosa could find no one to feed the pigs, Agatha gladly volunteered. During that time, there were 165 sisters and novices, eight postulants, and 75 students' a in the Academy. There were also 97 head of cattle.

 Agatha made simple vows on February 13, 1926, receiving the name of Sr. M. Clodesindis. She made her final profession on February 14, 1931. Sr. M. Clodesindis served at Clyde, Mundelein, Tucson, and Kansas City. She did a variety of tasks as well, including cooking, sewing, AB, gardening, painting, and butchering. In her last years at Clyde she worked in the packing room and printery. She came to St. Benedict Health Care Center in December, 1988.

The most enduring memory of Sr. M. Clodesindis is as a woman of prayer. Her hours of adoration before the Blessed Sacrament were times of great joy. Until she was no longer able to do so, she would wheel herself to chapel many times during the day. She prayed the rosary each day at 4:00 pm for all the sisters. Whenever anyone did a favor for her, she promised to pray a rosary for her. In one note to a superior, she promised to pray fifty rosaries for her.

Sr. M. Clodesindis was unable to recover from the flu that was making the rounds of the community. On the day of her death, the chaplain, who spoke German, was asked to pray for her, and he graciously consented. She was strengthened at the hour of her death, on April 11, 1999, with the sacrament of the anointing and a blessing in German as the sisters prayed at her bedside.