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Hispanic and Latino (Latina is the feminine) are often used interchangeably for people of Latin American descent living in the U.S. Latinx (plural Latinxs) is a gender-inclusive term; use it in direct quotes, names of organizations, and for any source who prefers it. When appropriate, use a more specific term, such as Mexican American, Cuban American, Puerto Rican.
Chicano (Chicana) is used for a U.S. citizen or inhabitant of Mexican descent, a Mexican American, but is rarely used today.
These terms have different meanings and varying degrees of acceptance among those of Spanish heritage; use only for individuals who prefer them.
Caution should be exercised to ensure that the usage fits the context.