Most biologists I know think that we have not answered any of the big questions (e.g. how did life start?, why do we age?, how did consciousness arise, just to name very, very few), or at least not anywhere near completion. I have a lot of respect for Carl Woese who discovered Archaea and made so many important contributions to biology, but I really do not know who he was taking about, who thought we had answered all the questiomns and just needed to fill in the “details”. In any case, it’s all details.