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1 M. A. Ishak, 2 C. A. Omar
1 Department of Animal Resources, College of Agriculture, University of Baghdad, 2 Department of Animal production, Faculty of Agricultural Sciences, University of Sulaimani
DOI: https://doi.org/10.17656/jzs.10325
Abstract:
This study was conducted to investigate the influence of testosterone enanthate
injection on some productive characteristics of Karadi lambs. This experiment was
carried out at the Sheep Farm, belong to the Faculty of Agricultural Sciences, University
of Sulaimani, Bakrajo. Thirty six Karadi ram lambs, aged 3-4 months and average live
weight of 28.7±3.8 kg were randomly divided into three equal groups. Six ram lambs from
each group were castrated using elastrator and rubber ring, two weeks before beginning
of the experiment. First group was left as control group without treatment (T1). The
second group (T2) was injected weekly with 200 mg of testosterone enanthate (TE)/ram
lamb. The third group (T3) was injected with 400 mg TE/ram lamb weekly until the
termination of the experiment. The TE injections as anabolic agent were given weekly to
each treated lamb to investigate its effect on some productive and physiological traits as
well as their residual effect, over the period from 18th May to 30th August 2010. Lambs
were fed as (3%) of live body weight. The allowance was readjusted at weekly intervals
according to live weight. Live body weight (LBW)(Kg), live weight gain(LWG)(%),
average daily gain (ADG) (gm/day), dry matter intake (DMI)(gm/day) and feed
conversion ratio (FCR)(gm DMI/gm gain) were determined. Results indicated that ADG
of intact lambs in the control group, low and high level of TE groups, were higher than
the castrated lambs at 4 months of age. The castrated lambs in T2 had higher ADG at 4,
5, 6, 7 and 8 months of age as compared with castrated lambs in T1 and T3 groups.
Higher DMI was recorded for the intact lambs of the control, low and high level of TE in
comparison with castrated lambs. Results revealed that castrated lambs of the control
group had higher FCR at 4,5,6 and 8 months of age as compared to intact lambs (4.06 vs.
3.46, 6.56 vs. 6.41 , 6.96 vs. 5.85 and 5.96 vs. 5.27 gm DMI /gm gain), while the FCR
increased in the intact lambs treated with 200 mg TE as compared to castrated lambs at
4,5,6 and 8 months of age (4.00 vs. 3.69, 4.94 vs. 3.93, 5.62 vs. 4.14 and 6.47 vs. 5.44 gm
DMI/gm gain), respectively. We concluded that castrated lambs treated with 200 mg TE
have higher ADG as compared with other experimental groups.
Keywords: Karadi ram; castrated lambs; intact lambs; TE; ADG; DMI.
References
1-G.O. Borazan, H. Karagul, S. Çelik, N. Ünal, M. Pekcan, and T. Sel, "Determination of
zeranol residues and the serum testosterone oestrogene and progesterone levels in lambs
around Ankara region", Ankara Univ., Vet. Fak. Derg., 54, pp. 7-10, (2007).
2- J.T. Sanderson, "The steroid hormone biosynthesis pathway as a target for endocrine
disrupting chemicals", Toxicol Sci., 94, pp.3-21, (2006).
3- A.S. Clark, and L.P. Henderson, "Behavioral and physiological responses to anabolic-
androgenic steroids", Neurosci. Biobehav. Rev., 27(5), pp.413-436, (2003).
4- T.M. Williams, A.J. Kind, W.G. Hyde, and D.W. Hill, "Characterization of urinary
metabolites of testosterone, methyltestosterone, mibolerone and boldenone in greyhound
dogs", J. Vet. Pharmacol. Therap., 23, pp.121–129, (2000).
5- Canadian Cattlemen’s Association (CCA) and Beef Information Centre(BIC), Available
at: www.cattle.ca; www.beefinfo.org, (2001).
6- A.F. Dixson, "Primate sexuality: Comparative studies of the prosimians, monkeys, apes
and human beings" Oxford University Press, New York, (1998).
7- R.J. Nelson, "Introduction to Behavioral Endocrinology", 3rd ed., Sunderland, MA,
Sinauer Associates, (2005).
8- J.C. Wingfield, R.E. Hegner, A.M. Dufty, and G.F. Ball, "The “challenge hypothesis”:
Theoretical implications for patterns of testosterone secretion, mating systems, breeding
strategies", American Naturalist, 136, pp.829-846, (1990).
9- R.F. Oliveira, "Social modulation of androgens in vertebrates: mechanisms and function",
Advances in the Study of Behavior, 34, pp.165–239, (2004).
10- H.A. Harper, "Review of Physiological Chemistry", Lange Medical Pub., Los Altos,
California, (1969).
11- F.N. Andrews, W.M. Beeson, and C. Harper, "The effect of stilbestrol and testosterone
on the growth and fattening of lambs", J. Anita. Sci., 8, pp.578-582, (1949).
12- A.L. Pope, C.C. O'Mary, W.E. Botterman, R.W. Bray, and L.E. Casida, "The effect of
certain steroid hormones on the growth, fattening and carcass quality of heavy lambs", J.
Anim. Sci., 9, pp.680(Abstract), (1950).
13- C.C. O'Mary, A.L. Pope, G.G. Wilson, R.W. Bray, and L.E. Casida, "Effects of
diethylstilbestrol, testosterone and progesterone on growth and fattening and certain
carcass characteristics of western lambs", J. Anita. Sci., 11, pp.656-673, (1952).
14- M.J. Burris, R. Bogart, and A.W., Olives, "Alteration of daily gain, feed efficiency and
carcass characteristics in beef cattle with male hormones", J. Anita. Sci., 12, pp.740-746,
(1953).
15- E.F. Johnston, F. Hudson, R. Bogart, and J. Kaufrues, "Retention of injected testosterone
in the meat of adult ewes", J. Anim. Sci., 15(1), pp.185-187, (1956).
16- E. Weimann, and W. Kiess, "Principles and clinical significance of insulin-like growth
factors somatomedins", Klin.Wochenschr., 68(20), pp.985-1002, (1990).
17- A. Boge, H. Sauerwein, and H.H. Meyer, "IGF-I and insulin receptors in bovine skeletal
muscle: comparisons of different developmental ages, two different B genotypes and
various individual muscles", Exp. Clin. Endocrinol. Diabetes, 103(2), pp.99-104, (1995).
18- J.P. Thissen, J.M. Ketelslegers, and L.E., Underwood, "Nutritional regulation of the
insulin-like growth factors", Endocr. Rev., 15(1), pp.80-101, (1994).
19- R.A. Frost, C.H. Lang, and M.C. Gelato, "Transient exposure of human myoblasts to
tumor necrosis factor-alpha inhibits serum and insulin-like growth factor-I stimulated
protein synthesis" J. Endocrin., 138(10), pp.4153-4159, (1997).
20- M. Pfaffl, F. Schwarz, and H. Sauerwein, "Quantification of insulin-like growth factor-1
(IGF-1) mRNA: modulation of growth intensity by feeding results in inter- and intra-
tissue-specific differences of IGF-1 mRNA expression in steers", Exp. Clin. Endocrinol.
Diabetes, 106(6), pp.514-521, (1998b).
21- H. Sauerwein, and H.H.D. Meyer, "Androgen and estrogen receptors in bovine skeletal
muscle: Relation to steroid-induced allometric muscle growth", J. Anim. Sci., 67, pp.206-
212, (1989).
22- C.I. Wong, Z.X. Zhou, M. Sar, and E.M. Wilson, "Steroid requirement for androgen
receptor dimerization and DNA binding. Modulation by intramolecular interactions
between the NH2-terminal and steroid-binding domains", J. Biol. Chem., 268(25),
pp.19004-19012, (1993).
23- O.E. Rooyackers, and K.S. Nair, "Hormonal regulation of human muscle protein
metabolism", Annu. Rev. Nutr., 17, pp.457-485, (1997).
24- R.J. Urban, "Effects of testosterone and growth hormone on muscle function", J. Lab.
Clin. Med., 134(1), pp.7-10, (1999).
25- K. Junkmann, "Long-acting steroids in reproduction", Recent Progr. Hormone Res., 13,
pp.389-419, (1957).
26- R. Hickson, S. Czerwinski, M. Falduto, and A. Young, "Glucocorticoid antagonism by
exercise and androgenic-anabolic steroids", Med. Sci. Sports Exerc., 22(3), pp.331–40,
(1990).
27- R. Singh, J. Artaza, W. Taylor, N. Gonzalez-Cadavid, and S. Bhasin, "Androgens
stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent
cells through an androgen receptor-mediated pathway", Endocrinology, 144(11),
pp.5081-5088, (2003).
28- E. Schroeder, A. Vallejo, and L. Zheng, "Six-week improvements in muscle mass and
strength during androgen therapy in older men", J. Gerontola. Biol. Sci. Med. Sci.,
60(12), pp.1586–1592, (2005).
29- D.L. Hancock, J.F. Wagner, and D.B. Anderson, "Effect of estrogens and androgens on
animal growth", In: A.M. Pearson and T.R. Dutson, (Ed.), Growth regulation in farm
animals, Elsevier Science Publishers, Essex, U.K., pp.255-297, (1991).
30- J.P.C. Greyling, and G.J. Taylor, "The effect of the anabolic agent, nandrolone laurate,
on certain production and reproduction parameters in ram lambs, under intensive and
extensive feeding regimes", S. Afr. J. Anim. Sci., 29(3), pp.179-188, (1999).
31- E. J. Squires, "Applied Animal Endocrinology", CABI Publishing. Book, ISBN 0 85199
594 2, pp.66-120, (2003).
32- B.D. Schanbacher, J.D. Crouse, and C.L. Ferrell, "Testosterone Influences on Growth,
Performance, Carcass Characteristics and Composition of Young Market Lambs", J.
Anim. Sci., 51(3), pp.685-691, (1980).
33- J.A. Jacobs, R.A. Field, M.P. Botkin, C.C. Kaltenbach, and M.L. Riley, "Effects of
Testosterone Enanthate on Lamb Carcass Composition and Quality", J. Anim. Sci., 34,
pp.30-36, (1972).
34- XLstat., 7.5.2, www.xlstat.com, (2010).
35- D.B. Duncan, "Multiple ranges and multiple F test", Bio metrics, 11, pp.1-12, (1955).
36- A. Trenkle, "Plasma levels of growth hormone, insulin and plasma protein-bound iodine
in finishing cattle", J. Anim. Sci., 31, pp.389-393, (1970).
37- B. Nazli, H. Olak, A. Aydin, and H. Hampikyan, "The Presence of Some Anabolic
Residues in Meat and Meat Products Sold in Üstanbul", Turk J. Vet. Anim. Sci., 29,
pp.691-699, (2005).
38- B.D. Schanbacher, and J.J. Ford, "Luteinizing hormone, testosterone, growth and carcass
responses to sexual alteration in the ram", J. Anim. Sci., 43, pp.638-643, (1976).
39- B.D. Schanbacher, "Testosterone regulation of luteinizing hormone and follicle
stimulating hormone secretion in young male lambs", J. Anim. Sci., 51, pp.679-684,
(1980b).
40- S.G. Haddad, M.Q. Husein, and R.W. Sweidan, "Effects of castration on growth
performance and carcass characteristics of Awassi lambs fed high concentrate diet",Small
Rum. Res., 65(1-2), pp.149-153, (2005).
41- P.J. Buttery, and P.A. Sinnett-Smith, "The mode of action of anabolic agents with special
reference to their effects on protein metabolism-some speculations", In: J. F. Roche and
D. O’Callaghan (Ed.), Manipulation of Growth in Farm Animals. Martinus Nijhoff
Publishers, Boston, MA, pp.211-228, (1984).
42- S.K. Duckett, and J.G. Andrae, "Implant strategies in an integrated beef production
system", J. Anim. Sci., 79 (Suppl. E.), pp.110-117, (2001).
43- S.S.R. Al-Muhirat, "Residues of anabolic steroids in meat", University of
Damascus, College of engineering agriculture, Food Science Department, Ph.D. thesis,
(2005).
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