Theileria

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Theileriases are a group of tickborne diseases caused by Theileria spp. A large number of Theileria spp are found in domestic and wild animals in tick-infested areas. T. microti is responsible for the disease human theileriosis, similar to babesiosis, a malaria-like disease which also causes fever and hemolysis. (Wiki)

The most important species affecting cattle and sheep are T parva, T annulata, T lestoquardi, T lowenshuni, and T uilenbergi.

Both Theileria and Babesia are Piroplasmorina. Although Babesia are primarily parasites of RBCs, Theileria use WBCs and RBCs for completion of their life cycle in mammalian hosts.

The parasite is transmitted in the saliva of infected ticks. Sporozoites invade leukocytes and, within a few days, develop to schizonts. Parasite multiplication occurs predominantly within the host WBCs, and some species multiply mainly in RBCs.

Theileria causes the host WBC to divide and at each cell division the parasite also divides. Thus, the parasitized cell population expands and becomes disseminated throughout the lymphoid system. Later in the infection, RBCs become piroplasms.

In animals fever occurs 7–10 days after parasites are introduced by feeding ticks and continues throughout the course of infection. Fevers may reach >106°F (41°C). Anemia is not a major diagnostic sign (as it is in babesiosis) because there is minimal division of the parasites in RBCs, and therefore no massive destruction of them. (Merck Veterinary Manual)

Babesiosis

Mary J. Homer,1 Irma Aguilar-Delfin,2 Sam R. Telford, III,3 Peter J. Krause,4 and David H. Persing1,*

Link to Full Article Here- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC88943/





Last Updated- April 2019

Lucy Barnes

AfterTheBite@gmail.com