Khurana VG, Teo C, Kundi M, Hardell L, Carlberg M.

Australian National University, Australia. vgkhurana@gmail.com

Abstract

The debate regarding the health effects of low-intensity electromagnetic radiation from sources such as power lines, base stations, and cell phones has recently been reignited. In the present review, the authors attempt to address the following question: is there epidemiologic evidence for an association between long-term cell phone usage and the risk of developing a brain tumor? Included with this meta-analysis of the long-term epidemiologic data are a brief overview of cell phone technology and discussion of laboratory data, biological mechanisms, and brain tumor incidence.

In order to be included in the present meta-analysis, studies were required to have met all of the following criteria: (i) publication in a peer-reviewed journal; (ii) inclusion of participants using cell phones for > or = 10 years (ie, minimum 10-year "latency"); and (iii) incorporation of a "laterality" analysis of long-term users (ie, analysis of the side of the brain tumor relative to the side of the head preferred for cell phone usage). This is a meta-analysis incorporating all 11 long-term epidemiologic studies in this field.

The results indicate that using a cell phone for > or = 10 years approximately doubles the risk of being diagnosed with a brain tumor on the same ("ipsilateral") side of the head as that preferred for cell phone use. The data achieve statistical significance for glioma and acoustic neuroma but not for meningioma.

The authors conclude that there is adequate epidemiologic evidence to suggest a link between prolonged cell phone usage and the development of an ipsilateral brain tumor.

ndian J Cancer. 2009 Jan-Mar;46(1):5-12.

11の長期疫学研究のメタ分析。10年以上携帯電話を使っていると、携帯電話側の脳に神経膠腫(グリア細胞由来の腫瘍)ができるリスクが携帯電話を使わない側の脳の2倍という結果がでた。これをCNNが報道した。確かにすごいことだが、携帯電話を使わない人と比べて2倍になるという話ではない。また、携帯電話の使用頻度等は質問紙による回想データに基づいているという大きな制約がある。やはり十分信頼できる研究ではない。後ろ向きの疫学研究のメタ分析。

Cell phones and tumor: still in no man's land.

Kohli DR, Sachdev A, Vats HS.

Department of Internal Medicine, Government Medical College and Hospital, Sector 32, Chandigarh-160 030, India.

Abstract

The use of cell phones is increasing worldwide at a phenomenal pace. While cellular communication has dramatically influenced our lifestyle, its impact on human health has not been completely assessed. Widespread concern continues in the community about the deleterious effects of radiofrequency radiations (with which cell phones operate) on human tissues and the subsequent potential for carcinogenesis. A detailed survey of published studies researching this question was done in preparation of this manuscript. Included in the survey were case reports, in vitro studies, population based retrospective studies and other investigations. The database of indexed journals was searched for key words like 'cell phone', 'radiation', 'cancer' and 'radio waves'. Guidelines issued by the World Health Organization, federal and technical authorities, Institute of Electrical and Electronic Engineers and the International Commission for Non-Ionizing Radiation Protection were reviewed. The evaluation of current evidence provided by various studies to suggest the possible carcinogenic potential of radiofrequency radiation is inconclusive. This risk assumes significance in light of the burgeoning number of people who are continually exposed to the high frequency radiation from cell phones and towers that serve as receiving and transmitting stations. The aim of this review is to identify limitations in past studies, present available data for consideration, and identify gaps in the current knowledge base. This will provide impetus and direction for further research and allow informed decisions pertaining to cell phone use to be made.

携帯電話と癌が関係しないという研究

Neuro Oncol. 2010 Nov;12(11):1147-51. Epub 2010 Jul 16.

Brain cancer incidence trends in relation to cellular telephone use in the United States.

Inskip PD, Hoover RN, Devesa SS.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Executive Plaza South, Room 7052, Bethesda, MD 20892, USA. inskippe@mail.nih.gov

Abstract

The use of cellular telephones has grown explosively during the past two decades, and there are now more than 279 million wireless subscribers in the United States. If cellular phone use causes brain cancer, as some suggest, the potential public health implications could be considerable. One might expect the effects of such a prevalent exposure to be reflected in general population incidence rates, unless the induction period is very long or confined to very long-term users. To address this issue, we examined temporal trends in brain cancer incidence rates in the United States, using data collected by the Surveillance, Epidemiology, and End Results (SEER) Program. Log-linear models were used to estimate the annual percent change in rates among whites. With the exception of the 20-29-year age group, the trends for 1992-2006 were downward or flat. Among those aged 20-29 years, there was a statistically significant increasing trend between 1992 and 2006 among females but not among males. The recent trend in 20-29-year-old women was driven by a rising incidence of frontal lobe cancers. No increases were apparent for temporal or parietal lobe cancers, or cancers of the cerebellum, which involve the parts of the brain that would be more highly exposed to radiofrequency radiation from cellular phones. Frontal lobe cancer rates also rose among 20-29-year-old males, but the increase began earlier than among females and before cell phone use was highly prevalent. Overall, these incidence data do not provide support to the view that cellular phone use causes brain cancer.

アメリカの大規模調査。27900万人のデータ。1992年から2006年で、年齢、脳腫瘍の部位などを分析したもの。携帯電話の契約者は92年から急速に伸びているが、脳腫瘍の患者は増えていない。特に、携帯電話の電波にさらされる頭頂側頭部や小脳の癌が増加していないので、携帯電話と脳腫瘍との関係は否定的である。