タートチェりーの研究をPubMedで"Human"と"Randomized Controlled Trial"で検索すると、4つの論文が見つかり、そのうち、2つは筋肉痛を抑制できたという。ただ、出版バイアス(ポジティブな結果は報告されるが、ネガティブな結果は報告されない)を考慮すると、タートチェリーに筋肉痛の低減効果があると結論づけるのは時期尚早であろう。

Concerning the effect of tart cherry, there are 4 papers in PubMed filtered by "Humans" and "Randomized Controlled Trial". Two researches confirmed the effect of reducing muscle pain. Considering with the publication bias ( the positive results are published more frequently than the negative results ), it is too early to conclude that the tart cherry juice reduces muscle pain.

Scand J Med Sci Sports. 2010 Dec;20(6):843-52. doi: 10.1111/j.1600-0838.2009.01005.x.

Influence of tart cherry juice on indices of recovery following marathon running.

Howatson G, McHugh MP, Hill JA, Brouner J, Jewell AP, van Someren KA, Shave RE, Howatson SA.

School of Psychology and Sport Sciences, Northumbria University, Newcastle upon Tyne, UK. glyn.howatson@northumbria.ac.uk

Abstract

This investigation determined the efficacy of a tart cherry juice in aiding recovery and reducing muscle damage, inflammation and oxidative stress. Twenty recreational Marathon runners assigned to either consumed cherry juice or placebo for 5 days before, the day of and for 48 h following a Marathon run. Markers of muscle damage (creatine kinase, lactate dehydrogenase, muscle soreness and isometric strength), inflammation [interleukin-6 (IL-6), C-reactive protein (CRP) and uric acid], total antioxidant status (TAS) and oxidative stress [thiobarbituric acid reactive species (TBARS) and protein carbonyls] were examined before and following the race. Isometric strength recovered significantly faster (P=0.024) in the cherry juice group. No other damage indices were significantly different. Inflammation was reduced in thecherry juice group (IL-6, P<0.001; CRP, P<0.01; uric acid, P<0.05). TAS was ~10% greater in the cherry juice than the placebo group for all post-supplementation measures (P<0.05). Protein carbonyls was not different; however, TBARS was lower in the cherry juice than the placebo at 48 h (P<0.05). The cherry juice appears to provide a viable means to aid recovery following strenuous exercise by increasing total antioxidative capacity, reducing inflammation, lipid peroxidation and so aiding in the recovery of muscle function.

© 2009 John Wiley & Sons A/S.

Br J Sports Med. 2006 Aug;40(8):679-83; discussion 683. Epub 2006 Jun 21.

Efficacy of a tart cherry juice blend in preventing the symptoms of muscle damage.

Connolly DA, McHugh MP, Padilla-Zakour OI, Carlson L, Sayers SP.

Human Performance Laboratory, University of Vermont, Burlington, VT 05405, USA. Declan.Connolly@uvm.edu

Abstract

Numerous antioxidant and anti-inflammatory agents have been identified in tart cherries.

To test the efficacy of a tart cherry juice blend in preventing the symptoms of exercise induced muscle damage.

This was a randomised, placebo controlled, crossover design. Fourteen male college students drank 12 fl oz of a cherry juice blend or a placebo twice a day for eight consecutive days. A bout of eccentric elbow flexion contractions (2 x 20 maximum contractions) was performed on the fourth day of supplementation. Isometric elbow flexion strength, pain, muscle tenderness, and relaxed elbow angle were recorded before and for four days after the eccentric exercise. The protocol was repeated two weeks later with subjects who took the placebo initially, now taking the cherry juice (and vice versa). The opposite arm performed the eccentric exercise for the second bout to avoid the repeated bout protective effect.

Strength loss and pain were significantly less in the cherry juice trial versus placebo (time by treatment: strength p<0.0001, pain p = 0.017). Relaxed elbow angle (time by treatment p = 0.85) and muscle tenderness (time by treatment p = 0.81) were not different between trials.

These data show efficacy for this cherry juice in decreasing some of the symptoms of exercise induced muscle damage. Most notably, strength loss averaged over the four days after eccentric exercise was 22% with the placebo but only 4% with the cherry juice.

この研究は筋肉痛が主観評価で、統制群と実験群の実験開始時の筋肉痛レベルに有意差があり、群が均質でないという大きな欠点がある。

This study has some limitations. Baseline score( subjective pain) was different between placebo and

cherry group. --- Two groups was not completely equivalent. . Reported score is subjective. So, there was a possibility that the flavor or taste had some effect.

J Int Soc Sports Nutr. 2010 May 7;7:17.

Efficacy of tart cherry juice in reducing muscle pain during running: a randomized controlled trial.

Kuehl KS, Perrier ET, Elliot DL, Chesnutt JC.

Department of Medicine, Oregon Health & Science University, Portland, OR, USA, 97239. kuehlk@ohsu.edu.

Abstract

Long distance running causes acute muscle damage resulting in inflammation and decreased force production. Endurance athletes use NSAIDs during competition to prevent or reduce pain, which carries the risk of adverse effects. Tart cherries, rich in antioxidant and anti-inflammatory properties, may have a protective effect to reduce muscle damage and pain during strenuous exercise. This study aimed to assess the effects of tart cherry juice as compared to a placebo cherry drink on pain among runners in a long distance relay race.

The design was a randomized, double blind, placebo controlled trial. Fifty-four healthy runners (36 male, 18 female; 35.8 +/- 9.6 yrs) ran an average of 26.3 +/- 2.5 km over a 24 hour period. Participants ingested 355 mL bottles oftart cherry juice or placebo cherry drink twice daily for 7 days prior to the event and on the day of the race. Participants assessed level of pain on a standard 100 mm Visual Analog Scale (VAS) at baseline, before the race, and after the race.

While both groups reported increased pain after the race, the cherry juice group reported a significantly smaller increase in pain (12 +/- 18 mm) compared to the placebo group (37 +/- 20 mm) (p < .001). Participants in thecherry juice group were more willing to use the drink in the future (p < 0.001) and reported higher satisfaction with the pain reduction they attributed to the drink (p < 0.001).

Ingesting tart cherry juice for 7 days prior to and during a strenuous running event can minimize post-run muscle pain.