10 PROBIOTICS PREMIX

Composition   100B CFU/g

1.Bacillus coagulans BC99 20.0  BCFU/g

2.Lactobacillus paracasei LC86 12.0  BCFU/g

3.Lactobacillus acidophilus LA85 12.0  BCFU/g

4.Bifidobacterium lactis BLa80 12.0  BCFU/g

5.Bifidobacterim bifidum BBi32 12.0  BCFU/g

6.Lactobacillus rhamnosus LRa05 10.0  BCFU/g

7.Bifidobacterium longum BL21 6.0   BCFU/g

8.Bifidobacterium breve BBr60 6.0   BCFU/g

9.Bifidobacterium infants BI45 6.0   BCFU/g

10.Lactobacillus reuteri LR08 4.0   BCFU/g

Bifidobacterium animalis subsp. lactis BLa80 has good gastrointestinal fluid tolerance and intestinal

adhesion ability, can reach the intestines and adhere to intestinal epithelial cells smoothly. 

Animal experiments show that Bla80 can effectively inhibit pathogenic bacteria such as Shigella flexneri and

increase the relative abundance of beneficial bacteria in the intestines of mice.

Lactobacillus acidophilus LA85 effectively inhibits Staphylococcus aureus, Escherichia coli and

Salmonella, significantly reduces the adhesion of pathogens to HT 29 cells, regulates the abundance of

intestinal flora such as Akkermansia, and regulates the body's immunity by affecting cytokine levels.

 Lactobacillus rhamnosus LRa05 resistant to gastric acid and bile, secretes lactic acid, lowers the pH in

the intestine, effectively inhibits pathogenic bacteria such as Staphylococcus aureus, Escherichia coli,

and Salmonella, helps promote the growth of other probiotic strains, and improves the balance of

intestinal flora.

 Bifidobacterium longum subsp. infantis BI45 is resistant to gastric acid and bile, ensuring the viability of

strains upon reaching the intestines, while also exhibiting strong adherence to intestinal epithelial cells. It

can inhibit common harmful bacterial populations in the intestines, promote the proliferation of

probiotics in the human body, and effectively enhance the structure of the intestinal microbiota.

Lacticaseibacillus paracasei LC86 can effectively promotes the proliferation of macrophages RAW264.7,

increases the phagocytosis index of RAW264.7 cells, promotes the production of TNF-α, IL-10 and other

cytokines, and plays an immune regulatory role. At the same time, this strain has a broad antibacterial spectrum and 

can effectively inhibit pathogenic bacteria such as Staphylococcus aureus, Escherichia coli,

Salmonella, Streptococcus mitis, and Klebsiella pneumoniae.

Bifidobacterium bifidum BBi32 has a certain tolerance to artificial gastric juice, and bile salts, and

adheres to intestinal epithelial cells. BBi32 also inhibits Escherichia coli, Staphylococcus aureus, and

Salmonella. Through animal experiments, it was found that BBi32 can promote the defecation volume,

number of fecal particles, and fecal moisture of constipated mice, increase the level of short-chain fatty

acids in the intestine of mice, and repair colon mucosal damage

Bifidobacterium longum subsp. Longum BL21 Remodeled Roseburia and Phosphatidylserine Levels and

Ameliorated Intestinal Disorders and liver Metabolic Abnormalities Induced by High-Fat Diet

Weizmannia coagulans BC99 has good tolerance to gastrointestinal juices and can smoothly reach 

the intestine. It can consume free oxygen in the intestine, making the intestinal environment conducive to the

growth of anaerobic strains such as Lactobacillus and Bifidobacterium, and increasing the number of

probiotic strains.

Bifidobacterium breve BBr60 has the important role in modulating key metabolic pathways, including

those involved in ABC transporters, arginine, proline, and tryptophan metabolism. Clinical trial results

demonstrated significant improvements in high-density lipoprotein (HDL) levels and reductions in total

cholesterol with BBr60 supplementation. Gastrointestinal symptoms and emotional states also

improved .

Probiotics information and benfits