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Nanomedical Engineering (2021~)
NIR Imaging (2014~)
Nanotoxicology/Nanomedicine (2006~)
Pharmaceutical Sciences (2006~)
Health Science/Education (2010~)
Nanomedical Engineering
Keywords: Nanoparticle, Protein, Secondary structure, β-sheet, Spectroscopy, FT-IR, Molecular dynamics
Sakaguchi N, Onoda A, Omata K, Umezawa M: Changes in protein secondary structure on surface of silica nanoparticles with different sizes. Langmuir, 41(23): 15143-15148 (June 2025) https://doi.org/10.1021/acs.langmuir.5c01606 [PubMed] [Open Access @ACS]
[Review] 梅澤雅和、上村真生、菊池明彦「ナノメディスンの機能デザイン」、科学フォーラム（東京理科大学）、2025(2): 4-7（2025年2月）[PDF]
Kaumbekova S, Sakaguchi N, Shah D, Umezawa M: Effect of gold nanoparticles on the conformation of bovine serum albumin: Insights from CD spectroscopic analysis and molecular dynamics simulations. ACS Omega, 9(50): 49283-49292 (Dec 2024) https://doi.org/10.1021/acsomega.4c06409 [PubMed] [Open Access @ACS]
Kaumbekova S, Sugita M, Sakaguchi N, Takahashi Y, Sadakane A, Umezawa M: Effect of acetonitrile on the conformation of bovine serum albumin. ACS Omega, 9(48): 47680-47689 (Nov 2024) https://doi.org/10.1021/acsomega.4c07274 [PubMed] [Open Access @ACS]
[Review] 梅澤雅和「脳の機能を支える血管周囲の病理を制御する―ナノ粒子と機械学習を活用したアプローチへ―」、科学フォーラム（東京理科大学）、2024(8): 34-39（2024年8月）[PDF]
Umezawa M, Itano R, Sakaguchi N, Kawasaki T: Infrared spectroscopy analysis determining secondary structure change in albumin by cerium oxide nanoparticles. Frontiers in Toxicology, 5: 1237819 (Sep 2023) https://doi.org/10.3389/ftox.2023.1237819 [PubMed]
[Review] 梅澤雅和「高分子ミセルの安定性評価」、『新規モダリティ医薬品のための新しいDDS技術と製剤化』（技術情報協会）第10章DDS製剤の機能性、物理的、化学的評価、第1節 pp.513-521、2023年1月）[Book]
Sakaguchi N, Kaumbekova S, Itano R, Amouei Torkmahalleh M, Shah D, Umezawa M: Changes in the secondary structure and assembly of proteins on fluoride ceramic (CeF3) nanoparticle surfaces. ACS Applied Bio Materials, 5(6): 2843-2850 (2022) https://doi.org/10.1021/acsabm.2c00239 [PubMed] [Open Access @ACS]
梅澤雅和「構造が材料の機能を決める」バイオマテリアル－生体材料－（日本バイオマテリアル学会）、39(4): 271 (2021) [日本語]
Changes in the folded structure of albumin due to gold nanoparticles determined by spectrometry and molecular dynamics reported in Kaumbekova et al. ACS Omega 9: 49283-49292 (2024)
Nonlinear changes in albumin conformation caused by the presence of an organic solvent acetonitrile reported in Kaumbekova et al. ACS Omega 9: 47680-47689 (2024)
"Changes in the secondary structure and assembly of proteins on fluoride ceramic (CeF3) nanoparticle surfaces" reported in Sakaguchi et al. ACS Appl. Bio Mater. (2022)
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