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Contact
Contact
INERIS, MIV/TEAM, MV/ESMI
UMR – I 02 SEBIO
Parc ALATA, BP2
5, rue Taffanel
60550 Verneuil en Halatte, France
+33 (0) 3 44 55 66 49
PhD Project
PhD Project
Effects of Bisphenol A substitutes at different scales of biological organization in stickleback fish: from biomarkers to population dynamics
Effects of Bisphenol A substitutes at different scales of biological organization in stickleback fish: from biomarkers to population dynamics
Biomarkers are necessary tools for establishing an early diagnosis of environmental risk. At INERIS, the development and validation of biomarkers in three-spined stickleback fish have provided a complementary set of biological indicators. However, the main limitations of these biomarker measurements for assessing ecosystem quality lie in extrapolating responses from one biological organizational scale to another, from the laboratory to the field, and from one species to another.
In practice, one of the only feasible means to bridge the gap between experimental observations and the protected biological unit is the use of mechanistic mathematical models. The development of such models requires available data on all biological levels to be linked: biomarkers, individual traits, and population dynamics.
Experiments conducted in recent years on bisphenol A substitutes (BPS and BPF) in the laboratory and in an experimental ecosystem (mesocosm) provide the necessary database for the development of these models. Indeed, during these experiments, measurements of early effect biomarkers on exposed fish were conducted in parallel with monitoring the effects on their population dynamics (individuals exposed throughout their lives and naive to the substances).
Thus, based on available experimental data and ongoing mathematical models, the aim of the phd is to link early effect biomarkers to effects on organism performance and subsequently to long-term consequences for populations.
Work experiences
Work experiences
October 2023
(in progress)
Ph.D Student in Ecotoxicology and Modelling
Supervisors: Dr. Rémy Beaudouin, Dr. Anne Bado Nilles
INERIS, Modelisation and Experimental Toxicology (TEAM) - Ecotoxicology of Substances and Environments (ESMI) - UMR-I 02 SEBIO
Project: Experimental and modelling approach in multiscale extrapolation effect on three spined sticklebacks (case study on bisphenol S and F)
Verneuil-en-Halatte, France
February 2023 August 2023
Research internship
INERIS, Institut National de l'Environnement Industriel et des Risques
Bibliography research on aquatic ecotoxicology
Statistical analyse on R langage (ANOVA)
DEB modelling on MCSIM software
DEB-IBM modelling on Netlogo Softare
Verneuil-en-Halatte, France
May 2021
July 2021
Assistant Engineer internship at the Direction Régionale de l'Environnement, de l'Aménagement et du Logement de la Nouvelle-Aquitaine (DREAL)
DREAL Nouvelle-Aquitaine, Direction Régionale de l'Environnement, de l'Aménagement et du Logement de la Nouvelle-Aquitaine
State of the art and inventory of "Avoid, Reduce, Compensate" (ERC) measures by protected species in the Nouvelle Aquitaine region and in the specific case of wind farms and photovoltaic power stations.
Poitiers, France
April 2019
August 2019
Farm work internship (polycultures/cattle breeders)
GAEC des deux rives & EARL HERVE THIERRY (49 122)
Farm work: feeding the cows, cleaning the cowshed, milking the cows, driving tractors
Learning about land management (soil improvement, crop rotation) and cattle breeders (sales, monitoring milk quality)
Farm management and accounting
Heubécourt-Harciourt $ Territoire du May sur Evres, France
Education and training
Education and training
2023
(in progress)
PhD Student in aquatic toxicology in ABIES school, Agriculture, Alimentation, Biologie, Environnement, Et Santé
AgroParisTech (Paris-Saclay, France)
2018-2023
(in progress)
Engineering school in Junia ISA, Institut Supérieur d’Agriulture: with Master’s Degree in Sustainable Management of Pollution (SMAP)
Graduated with honors
Catholic University (Lille, France)
2022
Master’s Degree (First Year) in UCT Prague with Specialization on Pollution Management
Erasmus Trip
Chemistry and Technology University (Prague, Czech Republic)
Language skills and Software
Language skills and Software
French: mother tongue
English: fluent (TOEIC)
Italian: basics (B1)
Software: Pack Office, Zotero, R-studio, GNU MCSim, Netlogo
Environments: Windows and Linux
Communications
Communications
Oral Communications
Blanche Goddyn, Anne Bado-Nilles, Cyril Turiès, Rémy Beaudouin. Impact du bisphenol s (bps) sur les populations d'epinoche à trois epines : analyse de donnees historiques en mesocosme a l'aide de modeles mathematiques (deb-ibm). Société Ecotoxicologique Fondamentale et Appliquée (SEFA), 3-4 juillet 2024, Besançon (France)
Posters
Publications
Publications
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