Benedicte TROUILLER

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Research interests

Dr Benedicte TROUILLER, PhD in Biology (University Paris XI), is a research scientist interested in lung toxicity, especially cell DNA damage induced after respiratory exposure. After working on DNA repair mechanisms in plants, her activities moved to animal models. During many years, nanoparticles lung toxicity was her focus, with a more attention on genetic toxicity. Recently, research projects evolved to asbestos related particles, such as cleavage fragments, or to air pollution impact on lung health.

Recent publications

• • Salieri B, Barruetabeña L, Rodríguez-Llopis I, Jacobsen NR, Manier N, Trouiller B, Chapon V, Hadrup N, Jiménez AS, Micheletti C, Merino BS, Brignon JM, Bouillard J, Hischier R. Integrative approach in a safe by design context combining risk, life cycle and socio-economic assessment for safer and sustainable nanomaterials. NanoImpact. 2021 Jul;23:100335. doi: 10.1016/j.impact.2021.100335. Epub 2021 Jun 19. PMID: 35559836.

  • Nelissen I, Haase A, Anguissola S, Rocks L, Jacobs A, Willems H, Riebeling C, Luch A, Piret JP, Toussaint O, Trouiller B, Lacroix G, Gutleb AC, Contal S, Diabaté S, Weiss C, Lozano-Fernández T, González-Fernández Á, Dusinska M, Huk A, Stone V, Kanase N, Nocuń M, Stępnik M, Meschini S, Ammendolia MG, Lewinski N, Riediker M, Venturini M, Benetti F, Topinka J, Brzicova T, Milani S, Rädler J, Salvati A, Dawson KA. Improving Quality in Nanoparticle-Induced Cytotoxicity Testing by a Tiered Inter-Laboratory Comparison Study. Nanomaterials (Basel). 2020 Jul 22;10(8):1430. doi: 10.3390/nano10081430. PMID: 32707981; PMCID: PMC7466672.

  • Trouiller B, Reliene R, Westbrook A, Solaimani P, Schiestl RH. Titanium dioxide nanoparticles induce DNA damage and genetic instability in vivo in mice. Cancer Res. 2009 Nov 15;69(22):8784-9. doi: 10.1158/0008-5472.CAN-09-2496. Epub 2009 Nov 3. PMID: 19887611; PMCID: PMC3873219.