2015

Peer-reviewed articles

    1. Bois FY., Gayraud G., 2015, Probabilistic Generation of Random Networks Taking into Account Information on Motifs Occurrence. Journal of Computational Biology Volume: 22 Issue: 1 Pages: 25-36.

    2. Goussen B., Beaudouin R., Dutilleul M., Buisset-Goussen A., Bonzom JM., Péry ARR. 2015. Energy-based modelling to assess effects of chemicals on Caenorhabditis elegans: A case study on uranium. Chemosphere. Volume 120, Pages 507–514

    3. Costanza Rovida, Nathalie Alépée, Anne M. Api, David A. Basketter, Frédéric Y. Bois, Francesca Caloni, Emanuela Corsini, Mardas Daneshian, Chantra Eskes, Janine Ezendam, Horst Fuchs, Patrick Hayden, Christa Hegele-Hartung, Sebastian Hoffmann, Bruno Hubesch, Miriam N. Jacobs, Joanna Jaworska, André Kleensang, Nicole Kleinstreuer, Jon Lalko, Robert Landsiedel, Frédéric Lebreux, Thomas Luechtefeld, Monica Locatelli, Annette Mehling, Andreas Natsch, Jonathan W. Pitchford, Donald Prater, Pilar Prieto, Andreas Schepky, Gerrit Schüürmann, Lena Smirnova, Colleen Toole, Erwin van Vliet, Dirk Weisensee, and Thomas Hartung. 2015. Integrated Testing Strategies (ITS) for safety assessment. ALTEX (32)1: 25-40.

    4. Dutilleul M, Goussen B, Bonzom J-M, Galas S, Réale D (2015) Pollution Breaks Down the Genetic Architecture of Life History Traits in Caenorhabditis elegans. PLoS ONE 10(2): e0116214. doi:10.1371/journal.pone.0116214

    5. Elgrabli D, Beaudouin R, Jbilou N, Floriani M, Pery A, Rogerieux F, Lacroix G. (2015) Biodistribution and Clearance of TiO2 Nanoparticles in Rats after Intravenous Injection. PLoS ONE 10(4): e0124490. doi:10.1371/journal.pone.0124490

    6. Willemin ME, Kadar A, de Sousa G, Leclerc E, Rahmani R, Brochot C. (2015) In vitro human metabolism of permethrin isomers alone or as a mixture and the formation of the major metabolites in cryopreserved primary hepatocytes. Toxicology in Vitro 29: 803–812.

    7. Truisi G., Di Consiglio E., Parmentier C., Savary C., Pomponio G., Bois F., Lauer B., Josse R., Hewitt P., Mueller S., Richert L., Guillouzo A., Testai E., 2015, Understanding the biokinetics of ibuprofen after single and repeated treatments in rat and human in vitro liver cell systems, Toxicology Letters, 233:172-186.

    8. Teng S, Barcellini-Couget S, Beaudouin R, Brochot C, Desousa G, Rahmani R, Pery A. BK/TD models for analyzing in vitro impedance data on cytotoxicity. 2015. Toxicology Letters. 235 (2): 96–106.

    9. Beaudouin, R; Goussen, B; Piccini, B; Augustine, S; Devillers, J; Brion, F; Pery, ARR. An Individual-Based Model of Zebrafish Population Dynamics Accounting for Energy Dynamics. 2015. PLOS ONE, 10 (5):10.1371/journal.pone.0125841.

    10. Leclerc E. Hamon J., Claude I., Jellali R., Naudot M., Bois F. Investigation of acetaminophen toxicity in HepG2/C3a microscale cultures using a system biology model of glutathione depletion. 2015. CELL BIOLOGY AND TOXICOLOGY, 31 (3): 173-185.

    11. Gould AL, Boye ME, Crowther MJ, Ibrahim JG, Quartey G, Micallef S, Bois FY. Joint modeling of survival and longitudinal non-survival data: current methods and issues. Report of the DIA Bayesian joint modeling working group. Stat Med. 2015. 34(14): 2181–2195.

    12. Bricks T, Hamon J, Fleury MJ, Jellali R, Merlier F, Herpe YE, Seyer A, Regimbeau JM, Bois F, and Leclerc E. Investigation of omeprazole and phenacetin first-pass metabolism in humans using a microscale bioreactor and pharmacokinetic models. Biopharmaceutics and Drug Disposition, 2015, 36(5): 275–293.

    13. Goussen B, Péry A, Bonzom JM, Beaudouin R. Trans-generational adaptation to pollution changes energy allocation in populations of nematodes. Environmental Science & Technology. 49 (20), pp 12500–12508

    14. Bellwon P, Truisi GL, Bois FY, Wilmes A, Schmidt T, Savary CC, Parmentier C, Hewitt PG, Schmal O, Josse R, Richert L, Guillouzo A, Mueller SO, Jennings P, Testai E, Dekant W. Kinetics and dynamics of cyclosporine A in three hepatic cell culture systems. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):62-78.

    15. Hamon J, Renner M, Jamei M, Lukas A, Kopp-Schneider A, Bois FY. Quantitative in vitro to in vivo extrapolation of tissues toxicity. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):203-16

    16. Pomponio G, Savary CC, Parmentier C, Bois F, Guillouzo A, Romanelli L, Richert L, Di Consiglio E, Testai E. In vitro kinetics of amiodarone and its major metabolite in two human liver cell models after acute and repeated treatments. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):36-51.

    17. Crean D, Bellwon P, Aschauer L, Limonciel A, Moenks K, Hewitt P, Schmidt T, Herrgen K, Dekant W, Lukas A, Bois F, Wilmes A, Jennings P, Leonard MO. Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):128-37.

    18. Wilmes A, Bielow C, Ranninger C, Bellwon P, Aschauer L, Limonciel A, Chassaigne H, Kristl T, Aiche S, Huber CG, Guillou C, Hewitt P, Leonard MO, Dekant W, Bois F, Jennings P. Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):117-27.

    19. Mueller SO, Dekant W, Jennings P, Testai E, Bois F. Comprehensive summary - Predict-IV: A systems toxicology approach to improve pharmaceutical drug safety testing. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):4-6.