2013

Peer-reviewed articles

1. Wilmes A, Limonciel A, Aschauer L, Moenks K, Bielow C, Leonard MO, Hamon J, Carpi D, Ruzek S, Handler A, Schmal O, Herrgen K, Bellwon P, Burek C, Truisi GL, Hewitt P, Di Consiglio E, Testai E, Blaauboer BJ, Guillou C, Huber CG, Lukas A, Pfaller W, Mueller SO, Bois FY, Dekant W, Jennings P. (2012). Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress. J Proteomics. 79C:180-194.

2. Diaz Ochoa JG, Bucher J, Péry ARR, Zaldivar Comenges JM, Niklas J, Mauch K. (2013). A multi-scale modeling framework for individualized, spatiotemporal prediction of drug effects and toxicological risk. Front. Pharmacol. 3:204

3. Choucha-Snouber L, Aninat C, Grsicom L, Madalinski G, Brochot C, Poleni PE, Razan F, Guillouzo CG, Legallais C, Corlu A, Leclerc E. (2013). Investigation of ifosfamide nephrotoxicity induced in a liver–kidney co-culture biochip. Biotechnol. Bioeng. 110:597–608.

4. Baudoin R, Prot JM, Nicolas G, Brocheton J, Brochot C, Legallais C, Benech H, Leclerc E. (2013). Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips. Xenobiotica 43:140–152.

5. Quignot N, Bois FY. (2013). A computational model to predict rat ovarian steroid secretion from in vitro experiments with endocrine disruptors. PLoS One. 8:e53891.

6. Rappaport SM, Kim S, Thomas R, Johnson BA, Bois FY, Kupper LL. (2013). Low-dose metabolism of benzene in humans: science and obfuscation. Carcinogenesis. 34:2-9.

7. Nkoa Onana DF, Mewoli B, Ouattara DA. (2013). Excitability in the host-pathogen interactions of HIV infection and emergence of viral load blips. J Theor Biol. 317:407-17.

8. Choucha Snouber L, Bunescu A, Naudot M, Legallais C, Brochot C, Dumas ME, Elena-Herrmann B, Leclerc E. Metabolomics-on-a-Chip of Hepatotoxicity Induced by Anticancer Drug Flutamide and Its Active Metabolite Hydroxyflutamide Using HepG2/C3a Microfluidic Biochips. Toxicol. Sci 132:8-20.

9. Zeman FA, Boudet C, Tack K, Floch Barneaud A, Brochot C, Péry ARR, Oleko A, Vandentorren S. 2013. Exposure assessment of phthalates in French pregnant women: Results of the ELFE pilot study. International Journal of Hygiene and Environmental Health 216, 271-279.

10. Beaudouin R, Péry ARR. 2013. Comparison of species sensitivity distributions based on population or individual endpoints. Environ. Toxicol. Chem. 32, 1173-1177.

11. Péry ARR, Schüürmann G, Ciffroy P, Faust M, Backhaus T, Aicher L, Mombelli E, Tebby C, Cronin MT, Tissot S, Andres S, Brignon JM, Frewer L, Georgiou S, Mattas K, Vergnaud JC, Peijnenburg W, Capri E, Marchis A, Wilks MF. 2013. Perspectives for integrating human and environmental risk assessment and synergies with socio-economic analysis. Sci. Total Environ. 456-457C:307-316.

12. Péry ARR, Brochot C, Zeman FA, Mombelli E, Desmots S, Pavan M, Fioravanzo E, Zaldívar JM. 2013. Prediction of dose-hepatotoxic response in humans based on toxicokinetic/toxicodynamic modeling with or without in vivo data: A case study with acetaminophen. Toxicol. Lett. 220, 26-34.

13. Geenen S, Yates JW, Kenna JG, Bois FY, Wilson ID, Westerhoff HV. 2013. Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione-depletion biomarkers ophthalmic acid and 5-oxoproline in humans and rats. Integr. Biol. 5(6), 877-88.

14. Ramirez T, Daneshian M, Kamp H, Bois FY, Clench MR, Coen M, Donley B, Fischer SM, Ekman DR, Fabian E, Guillou C, Heuer J, Hogberg HT, Jungnickel H, Keun HC, Krennrich G, Krupp E, Luch A, Noor F, Peter E, Riefke B, Seymour M, Skinner N, Smirnova L, Verheij E, Wagner S, Hartung T, van Ravenzwaay B, Leist M. 2013. Metabolomics in toxicology and preclinical research. ALTEX 30,209-25.

15. Coecke S, Pelkonen O, Leite SB, Bernauer U, Bessems JG, Bois FY, Gundert-Remy U, Loizou G, Testai E, Zaldivar JM. 2013. Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches. Toxicol. In Vitro 27, 1570-1577.

16. Zeise L, Bois FY, Chiu WA, Hattis D, Rusyn I, Guyton KZ. 2013. Addressing human variability in next-generation human health risk assessments of environmental chemicals. Environ. Health Perspect. 121, 23-31.

17. Rappaport SM, Johnson BA, Bois FY, Kupper LL, Kim S, Thomas R. 2013. Ignoring and adding errors do not improve the science. Carcinogenesis 34, 1689-1691.

18. Goussen B, Parisot F, Beaudouin R, Dutilleul M, Buisset-Goussen A, Péry ARR, Bonzom JM. 2013. Consequences of a multi-generation exposure to uranium on Caenorhabditis elegans life parameters and sensitivity. Ecotoxicology 22, 869-878.

19. De Kermoysan G, Péry ARR, Porcher JM, Beaudouin R. 2013. A non-invasive method based on head morphology to sex mature three-spined stickleback (Gasterosteus aculeatus L.) in rearing conditions. Math. Biosci. 244, 148-153.

20. Tebby C, Mombelli E. 2013. Modelling Structure Activity Landscapes with Cliffs: a Kernel Regression-Based Approach. Molecular Informatics 32, 609-623.

21. Bois F. 2013, Computational pharmacokinetics at a crossroads, In Silico Pharmacology 1:5.

22. de Kermoysan G, Joachim S, Baudoin P, Lonjaret M, Tebby C, Lesaulnier F, Lestremau F, Chatellier C, Akrour Z, Pheron E, Porcher JM, Péry ARR, Beaudouin R. 2013. Effects of bisphenol A on different trophic levels in a lotic experimental ecosystem. Aquatic Toxicology 144-145C,186-198.

23. Winkler DA, Mombelli E, Pietroiusti A, Tran L, Worth A, Fadeel B, McCall MJ. 2013. Applying quantitative structure-activity relationship approaches to nanotoxicology: Current status and future potential.Toxicology 313, 15-23.

24. Bonvallot N, Péry A, Lafon D, Boulanger G, Karg F, Mosqueron L, Ismert M, Guillossou G, Section Méthodologie d’évaluation des risques sanitaires de la SFSE, Glorennec P. 2013. Evaluation du risque chimique en santé-travail et en santé-environnement : objectifs et méthodes. Environnement, Risques, Santé 12, 434-441.

25. Péry A, Bonvallot N, El Yamani M, Boulanger G, Karg F, Mosqueron L, Ismert M, Guillossou G, Section Méthodologie d’évaluation des risques sanitaires de la SFSE, Glorennec P. 2013. Valeurs limites d’exposition professionnelles (VLEP), valeurs toxicologiques de référence (VTR) : objectifs et méthodes. Environnement, Risques, Santé 12, 442-449.

26. Bessems JG, Loizou G, Krishnan K, Clewell HJ 3rd, Bernasconi C, Bois F, Coecke S, Collnot EM, Diembeck W, Farcal LR, Geraets L, Gundert-Remy U, Kramer N, Küsters G, Leite SB, Pelkonen OR, Schröder K, Testai E, Wilk-Zasadna I, Zaldívar-Comenges JM. 2013. PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment: Recommendations from a joint EPAA - EURL ECVAM ADME workshop. Regul Toxicol Pharmacol. 68, 119-139.

Book Chapter

1. Péry ARR, Beaudouin R. 2013. Biology-based and population dynamics modeling in ecotoxicology. In Encyclopedia of Aquatic Ecotoxicology. Ferard JF and Blaise C eds. Springer, Dordrecht. p 205-210.