Publications current year

Peer-reviewed articles

1. Paré, A., Ratier, A., Desroziers, E., Mhaouty-Kodja, S., Chardon, K., & Zeman, F. (2026). Development of a generic Physiologically Based Pharmacokinetic (PBPK) model for female mouse including gestation: application to PFOA to link environmental levels to New Approaches Methodologies (NAMs) results for environmental risk assessment. Environmental Research, 123933. doi:https://doi.org/10.1016/j.envres.2026.123933

2. Pachoulide, C., Vogs, C., Ratier, A., Koster, J., Husøy, T., Vrijheid, M., . . . Kramer, N. I. (2026). A human next generation PBK model for PFOA. Environment International, 110161. doi:https://doi.org/10.1016/j.envint.2026.110161

3. Paré, A., Ratier, A., Mhaouty-Kodja, S., Chardon, K., & Zeman, F. (2026). Lifetime PBPK model for female mice from the prenatal to lactation period: New insights for neurodevelopmental risk assessment of methylmercury. Environmental Toxicology and Pharmacology, 124, 105024. doi:https://doi.org/10.1016/j.etap.2026.105024

4. Goddyn, B., Beaudouin, R., Palluel, O., Turies, C., Joachim, S., Blanquet, J.-P., . . . Bado-Nilles, A. (2026). Overall impacts of bisphenol S (BPS) on the three-spined stickleback (Gasterosteus aculeatus) in a mesocosm experiment: Relationships between biomarkers, life-history traits, and population-level effects. Ecotoxicology and Environmental Safety, 318, 120227. doi:https://doi.org/10.1016/j.ecoenv.2026.120227

5. Luijten, M., Herzler, M., Affourtit, F., Allen, D., Ashraf, M. W., Ball, N., Berggren, E., Berndt, S., Billat, P.-A., Cöllen, E., Colbourne, J., Corvaro, M., Currie, R., Diemar, M. G., Dirven, H., Dreser, N., Escher, S. E., Gardner, I., Gozalbes, R., … Leist, M. (2026). Stakeholder input towards further refinement and consolidation of the alternative safety profiling algorithm (ASPA) for next generation risk assessment (NGRA). ALTEX - Alternatives to Animal Experimentation. https://doi.org/10.14573/altex.2603121 

6. Smith NM, de Bruijn VMP, Vandebriel RJ, Hargitai R, Lumniczky K, Janssen AWF, Beekmann K, Usta B, Tigges J, Spruck C, Hurem S, Iulini M, Corsini E, Bado-Nilles A, Beaudouin R, Katsiadaki I, Cano I, Sebire M, Ayuk HS, Stojanovska V, Zenclussen AC, Blanc EB, Kerdine-Römer S, Lacerda R, Romão L, Monfort-Lanzas P, Gostner JM, Mposhi A, Turner JD, Del Favero G and Lindeman B (2026) New approach methodologies (NAMs) to support regulatory assessment of developmental immunotoxicity – a new PARC project. Front. Toxicol. 8:1740390. doi: https://doi.org/10.3389/ftox.2026.1740390

7. David, A., Lennon, S., Mercier, F., ... Zeman F, Blanc E, Antignac JP, Le Bizec B, Samson M. (2026). Mapping the human chemical exposome for public health. Nat Med. https://doi.org/10.1038/s41591-026-04289-7 

8. Brenner, D., K. Bernal, E. Sychrová, J. Kohoutek, S. Langouet, C. Tebby, R. Beaudouin, R. Boufalaas, J. Dairou, A., Tête, P., Babica, E. B. Blanc, I. Sovadinová, and P. A. Billat. (2026). 'Chemical fate in vitro: A physiological biokinetic (PBK) model for cell-based assays', ALTEX - Alternatives to Animal Experimentation. https://doi.org/10.14573/altex.2509261 

9. Beaudouin, R., Geffroy, F., Le Menach, K., Budzinski, H., Bodin, C., Dussauçoy, R., . . . Billat, P.-A. (2026). Physiologically based kinetics and toxicodynamic (PBK-TD) modelling in zebrafish embryos: A novel approach to assess endocrine disrupting chemicals acting on brain aromatase. Computational Toxicology, 100423. https://doi.org/10.1016/j.comtox.2026.100423

10. Piir, G., Sild, S., Tcheremenskaia, O., Di Consiglio, E., Henriksson, J., Gajewicz-Skretna, A., Mombelli, E., Roncaglioni, A., Maran, U. (2026). Perspective on applicability of data-driven machine learning computational new approach methodologies for hazard identification in chemicals risk assessment. Journal of Cheminformatics, 18(1), 57. https://doi.org/10.1186/s13321-026-01184-8

11. Billat, P.-A., Hansen, T., De Bruijn, V., Boufalaas, R., Stefano, S., Sosnowska, A., [...], Ratier, A., [...], Staal, Y. C. M. (2026). NAMs for closing knowledge gaps in assessment of respiratory uptake – a PARC project. Frontiers in Toxicology, Volume 8 - 2026. https://doi.org/10.3389/ftox.2026.1764276

12. Kruisselbrink, J. W., Minnema, [...], Ratier, A., Kumar, V., Engel, J. Engel, J. (2026). An exchange standard for FAIR PBK models in chemical risk assessment – A PARC community effort. Computational Toxicology, 39, 100426. https://doi.org/10.1016/j.comtox.2026.100426

13. El Mais, A. E. R., Brion, F., [...], Mombelli E., Bisson, M., Aït-Aïssa, S. (2026). In silico, in vitro, and in vivo profiling of endocrine activity and toxicity of selected oxygenated polycyclic aromatic compounds frequently encountered in PAH-contaminated soils. Environmental Pollution, 405, 128549. https://doi.org/10.1016/j.envpol.2026.128549