2016

Peer-reviewed articles

• 1. Leclerc E., Hamon J. and Bois FY. Investigation of ifosfamide and chloroacetaldehyde renal toxicity through integration of in vitro liver–kidney microfluidic data and pharmacokinetic-system biology models. J. Appl. Toxicol. 2016, Volume 36, Issue 2, pages 330–339.

  2. Fournier K, Tebby C, Zeman F, Glorennec P, Zmirou-Navier D, Bonvallot N. Multiple exposures to indoor contaminants: Derivation of benchmark doses and relative potency factors based on male reprotoxic effects. Regul Toxicol Pharmacol. 2016, Volume 74, Pages 23–30.

  3. Willemin ME, Desmots S, Le Grand R, Lestremau F, Zeman FA, Leclerc E, Moesch C, Brochot C. PBPK modeling of the cis- and trans-permethrin isomers and their major urinary metabolites in rats. Toxicology and Applied Pharmacology, 2016, 294: 65–77.

  4. De Sousa G., Teng S., Salle-Siri R., Pery A., Rahmani R. Prediction of the metabolic clearance of benzophenone-2, and its interaction with isoeugenol and coumarin using cryopreserved human hepatocytes in primary culture. Food and Chemical Toxicology, 2016, 90: p. 55-63.

  5. Nicoleta Suciu, Alice Tediosi, Philippe Ciffroy, Annette Altenpohl, Céline Brochot, Frederik Verdonck, Federico Ferrari, Elisa Giubilato, Ettore Capri, Gabriella Fait. Potential for MERLIN-Expo, an advanced tool for higher tier exposure assessment, within the EU chemical legislative frameworks. 2016, 562: 474-479.

  6. Benfenati E, Belli M, Borges T, Casimiro E, Cester J, Fernandez A, Gini G, Honma M, Kinzl M, Knauf R, Manganaro A, Mombelli E, Petoumenou MI, Paparella M, Paris P, Raitano G. Results of a round-robin exercise on read-across. SAR QSAR Environ Res. 2016 May 11:1-14.

  7. Péré H., Rascanu A., LeGoff J., Matta M., Bois F., Lortholary O., Leroy V., Launay O., Bélec L., ANRS EP24 study group. Herpes simplex virus type 2 (HSV-2) genital shedding in HSV-2-/HIV-1-co-infected women receiving effective combined antiretroviral therapy. Int J STD AIDS. Int J STD AIDS March 2016 vol. 27 no. 3 178-185.

  8. Golbamaki A, Benfenati E, Golbamaki N, Manganaro A, Merdivan E, Roncaglioni A, Gini G. New clues on carcinogenicity-related substructures derived from mining two large datasets of chemical compounds. Journal of Environmental Science and Health, Part C. Environmental Carcinogenesis and Ecotoxicology Reviews. 2016 Apr 2;34(2):97-113.

  9. Nicoulaud-Gouin V, Garcia-Sanchez L, Giacalone M, Attard J.C., Martin-Garin A., Bois FY. Identifiability of sorption parameters in stirred flow-through reactor experiments and their identification with a Bayesian approach. Journal of Environmental Radioactivity. 2016 162-163: 328-339.

  10. Teng S, Tebby C, Barcellini-Couget S, De Sousa G, Brochot C, Rahmani R, Pery AR. Analysis of real-time mixture cytotoxicity data following repeated exposure using BK/TD models. Toxicol Appl Pharmacol. 2016 Jun 15;305:118-126.

  11. Hinfray N, Tebby C, Garoche C, Piccini B, Bourgine G, Aït-Aïssa S, Kah O, Pakdel F, Brion F. Additive effects of levonorgestrel and ethinylestradiol on brain aromatase (cyp19a1b) in zebrafish specific in vitro and in vivo bioassays. Toxicol Appl Pharmacol. 2016 Aug 1;307:108-114.

  12. Ciffroy P, Alfonso B, Altenpohl A, Banjac Z, Bierkens J, Brochot C, Critto A, De Wilde T, Fait G, Fierens T, Garratt J, Giubilato E, Grange E, Johansson E, Radomyski A, Reschwann K, Suciu N, Tanaka T, Tediosi A, Van Holderbeke M, Verdonck F. Modelling the exposure to chemicals for risk assessment: a comprehensive library of multimedia and PBPK models for integration, prediction, uncertainty and sensitivity analysis - the MERLIN-Expo tool. Sci Total Environ. 2016 Volume 568, 15 October 2016, Pages 770-784.

  13. Fierens T, Van Holderbeke M, Standaert A, Cornelis C, Brochot C, Ciffroy P,Johansson E, Bierkens J. Multimedia & PBPK modelling with MERLIN-Expo versus biomonitoring for assessing Pb exposure of pre-school children in a residential setting. Sci Total Environ. Volume 568, 15 October 2016, Pages 785-793.

  14. Mirja Van Holderbeke, Tine Fierens, Arnout Standaert, Christa Cornelis, Céline Brochot, Philippe Ciffroy, Erik Johansson, Johan Bierkens. Assessing multimedia/multipathway exposures to inorganic arsenic at population and individual level using MERLIN-Expo. Volume 568, 15 October 2016, Pages 794-802

  15. Giubilato E, Radomyski A, Critto A, Ciffroy P, Brochot C, Pizzol L, Marcomini A. Modelling ecological and human exposure to POPs in Venice lagoon. Part I -Application of MERLIN-Expo tool for integrated exposure assessment. Sci Total Environ. Volume 565, 15 September 2016, Pages 961-976

  16. Radomyski A, Giubilato E, Ciffroy P, Critto A, Brochot C, Marcomini A. Modelling ecological and human exposure to POPs in Venice lagoon - Part II: Quantitative uncertainty and sensitivity analysis in coupled exposure models. Sci Total Environ. 2016 Volumes 569–570, 1 November 2016, Pages 1635–1649.

  17. Cote I, Andersen ME, Ankley GT, Barone S, Birnbaum LS, Boekelheide K, Bois FY, Burgoon LD, Chiu WA, Crawford-Brown D, Crofton KM, DeVito M, Devlin RB, Edwards SW, Guyton KZ, Hattis D, Judson RS, Knight D, Krewski D, Lambert J, Maull EA, Mendrick D, Paoli GM, Patel CJ, Perkins EJ, Poje G, Portier CJ, Rusyn I, Schulte PA, Simeonov A, Smith MT, Thayer KA, Thomas RS, Thomas R, Tice RR, Vandenberg JJ, Villeneuve DL, Wesselkamper S, Whelan M, Whittaker C, White R, Xia M, Yauk C, Zeise L, Zhao J, DeWoskin RS. The Next Generation of Risk Assessment Multi-Year Study- Highlights of Findings, Applications to Risk Assessment and Future Directions. Environ Health Perspect 124:1671–1682.

Book chapters

1. Mombelli E, Raitano G, Benfenati E. In Silico Prediction of Chemically Induced Mutagenicity: How to Use QSAR Models and Interpret Their Results. Methods Mol Biol. 2016;1425:87-105.

2. Bois FY, Brochot C. Modeling Pharmacokinetics. Methods Mol Biol. 2016;1425:37-62.

3. Paul Quindroit, Frédéric Y.·Bois, Céline Brochot. Exposome. YearBook Santé et environnement 2016 ; 201-204