Corentin Mit
Contact
INERIS, MIV/TEAM
Parc ALATA, BP 2
5, rue Taffanel
60550 Verneuil en Halatte, France
PhD Project
Biomarkers are known for being useful tools in risk assessment. They act like an early alarm system of the organism in response to exposition to pollutants. Nevertheless, risk assessment for the ecosystem should not only be limited to individual but should evaluate the risk for the whole population. The main limitation in biomarker measurements lies in the transition between cell to individual, and individual to population.
At INERIS, a lot has been done to fill this gap using a model organism, the Threespine Stickleback. In particular, a PBTK model has been built to evaluate the toxicokinetic of various xenobiotics in different fish, including Stickleback and numerous biomarkers have been developed to assess the quality of stickleback ecosystem. In parallel, EDCs (endocrine disruptor compounds) have been subject to an increasing source of interest at the institute, and among them, bisphenol A and its substitutes.
The aim of my PhD is to adapt the PBTK model of Threespine Stickleback to BPA and BPS, notably in terms of metabolization, and to link early effect biomarker responses with toxicodynamic building a PBTK-TD model. Expositions to BPA and BPS will be conducted to provide data and finally try to connect individual performances and biomarker responses.
Work experience
October 19
(in progress)
INERIS, Unit Models for Ecotoxicology and Toxicology - Verneuil-en-Halatte (60)
Ph.D Student Ecotoxicology and Toxicokinetic modelling
Project: Mechanistic modelling of the link between early effect biomarkers and impacts on populations on Threespine Stickleback.
Under the direction of Rémy Beaudouin (INERIS) and Anne Bado-Nilles (INERIS)
August 19
September 19
EDF R&D, National Hydraulics and Environment Laboratory - Chatou (78)
Research engineer
Project: Writing of an article based on the result of my internship.
"Macroinvertebrate drift density in relation to hydeopeaking conditions" (abstract submitted in November 19)
February 19
August 19
EDF R&D, National Hydraulics and Environment Laboratory - Chatou (78)
Intern Research engineer
Project: Description and quantification of macroinvertebrate drift in relation to hydropeaking condition.
Formatting a large dataset and statistical analysis with Rstudio software (GLM, fourth-corner method)
June 18
August 18
BMRS (Bantry Marine Research Station) - Bantry (Ireland)
Intern
Project: Expansion of a lumpfish farm.
Fish husbandry and daily care.
Education and training
October 2019
(in progress)
AgroParisTech - Paris (75)
Doctoral School ABIES (Agriculture Food Biology Environment Health)
Ph.D. Ecotoxicology
2016-2019
National school of agronomy – Toulouse and Rennes (France)
Master of Fisheries and Aquatic Sciences
2013-2016
Lycée Victor Hugo – Lycée Camille Guérin – Besançon and Poitiers (France)
Preparatory classes (Biology, Chemistry, Physics and Geology) for the national selective examination to french "Grandes Ecoles"
Language skills and software
French: mother tongue
English: upper intermediate level
Spanish: intermediate level
Software: Office (Access included), R-studio, Python, VBA (beginner)