Aya ASHRIN

Ph.D Student in experimental toxicology

Exposure of rats and lung, eye and epithelial cells simultaneously to different composition of smokes to develop a predictive tool listing the tested data and those found in the literature.

Thesis director P.Rotureau ;

Supervision by G, Lacroix, and G. Fayet

Verneuil-en-Halatte, France

INTERNSHIP : ALTERNATIVE (IN VIVO) TESTS TO CARCINOGENICITY STUDIES (IN PARTICULAR TRANSGENIC MODELS) : ADVANTAGES AND DISADVANTAGES, INTERPRETATION AND PLACE IN EUROPEAN REGULATIONS REACH AND CLP

(ANSES : 14 Rue Pierre et Marie Curie, 94700 Maisons-Alfort)

Bibliographic survey of alternative in vivo/vitro tests to the carcinogenicity study;

Writing of a report and of the dissertation in English; presentation of the project at unit meetings

Reach expert committees; participation in the STCM congress.

Supervision by E. Pasquier

INTERNSHIP: GENETIC AND EPIGENETIC IMPACT OF ENVIRONMENTAL FINE PARTICLES IN RELATION WITH THEIR CHEMICAL COMPOSITION ON HUMAN CORNEAL EPITHELIAL CELLS

(4 avenue de l’observatoire 75006 Paris)

ELISA, RT PCR, CELL CULTURE, MTT TEST, ARN EXTRACTION.

Supervision by S.Achard

FOREIGN INTERNSHIP: BIOREMEDIATION OF TOXIC COMPOUNDS FROM CONTAMINATED SITES:

(Universita delli studi di Milano Bicocca. 1 20126 MILANO ITALY.)

ARN 16S Extraction +RTQ PCR, bio-informatic.

Supervision by A. Franzetti