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Date de publication : Jul 03, 2020 8:35:41 AM
We are pleased to let you know that the final version of the article "Temperature effect on perfluorooctane sulfonate toxicokinetics in rainbow trout (Oncorhynchus mykiss): Exploration via a physiologically based toxicokinetic model" is now available online ! (https://doi.org/10.1016/j.aquatox.2020.10554)
Highlights
•PFAAs fate are still poorly understood in fish.
•Water temperature strongly influences the ADME mechanisms of toxic substances.
•PBTK model for rainbow trout accurately simulates PFOS ADME at different temperatures.
•Accounting for the influence of temperature on tissue–plasma partition coefficients significantly improved predicted in-organ PFOS concentrations.
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