New article by Alice Vidal exploring PFOS TK in trout

A PBTK model describing PFOS kinetics was calibrated for simultaneous uptake pathways. Fish growth was modeled to correct PFOS dilution in organs. PFOS was more eliminated by feces while urine was a minor excretion route. Gill absorption and excretion cannot be neglected. The enterohepatic cycle was not supported by model outputs.

Alice Vidal, Marc Babut, Jeanne Garric, Rémy Beaudouin. 2019. Elucidating the fate of perfluorooctanoate sulfonate using a rainbow trout (Oncorhynchus mykiss) physiologically-based toxicokinetic model, Science of The Total Environment, Volume 691, Pages 1297-1309.

https://doi.org/10.1016/j.scitotenv.2019.07.105