1. Complex: Trans-sialidase from Trypanosoma cruzi in complex with the Fab fragment of a neutralizing monoclonal IgG 13G9

• CATH

• Resolution: 3.4 Å

• Species: Trypanosoma cruzi

2. Antigen: Trypanosoma cruzi trans-sialidase

• structure length (residues): 648

• mutations: 11

• Uniprot

3. Antibody: neutralizing mAb IgG 13G9

• Isotype/subclass: IgG2

• Structure: Fab only

3.1 Heavy chain 

• structure length (residues): 222

• mutations: No

• disulfide bridges: 21-95, 145-200

• CDR (residue numbering): 

3.2 Light chain

• structure length (residues): 213

• mutations: No

• disulfide bridges: 23-87, 133-193

• CDR (residue numbering): 

RCSB PDB - 3OPZ - Trans-sialidase from Trypanosoma cruzi in complex with the Fab fragment of a neutralizing monoclonal IgG 13G9

Trans-sialidase from Trypanosoma cruzi in complex with an IgG 13G9 (310K, 37°C, 100 ns) >> RMSD, SASA, RMSF, Rg, H-bonds

Trans-sialidase from Trypanosoma cruzi in complex with an IgG 13G9 (311K, 38°C, 100 ns) >> RMSD, SASA, RMSF, Rg, H-bonds

Trans-sialidase from Trypanosoma cruzi in complex with an IgG 13G9 (312K, 39°C, 100 ns) >> RMSD, SASA, RMSF, Rg, H-bonds

Trans-sialidase from Trypanosoma cruzi in complex with an IgG 13G9 (313K, 40°C, 100 ns) >> RMSD, SASA, RMSF, Rg, H-bonds