1. Complex: Crystal structure of the West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab 

• CATH

• Resolution: 3 Å

• Species: West Nile virus 

2. Antigen: NS1, Flavivirus nonstructural protein 1 

• structure length (residues): 185

• mutations: No

• Uniprot

3. Antibody: 22NS1 mAb

• Isotype/subclass: IgG1k

• Structure: Fab + Fab

3.1 Heavy chain 

• structure length (residues): 217

• mutations: No

• disulfide bridges: 22-96, 144-199

• CDR (residue numbering): 31-33, 53, 95-98

3.2 Light chain

• structure length (residues): 213

• mutations: No

• disulfide bridges: 23-88, 134-194

• CDR (residue numbering): 30, 92, 94, 96 

RCSB PDB - 4OII : West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab

West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab (310K, 37°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab (311K, 38°C, 100 ns) >>   RMSD, SASA, RMSF, Rg, H-bonds

West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab (312K, 39°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab (313K, 40°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds