1. Complex: GM-CSF in complex with human auto-antibody F1

• CATH

• Resolution: 2 Å

• Species: H. sapiens

2. Antigen: Granulocyte-macrophage colony-stimulating factor,  GM-CSF,  colony-stimulating factor 2, CSF2 

• structure length (residues): 127

• mutations: No

• Uniprot

3. Antibody: auto-antibody F1 mAb

• Isotype/subclass: IgG1

• Structure: Fab only

3.1 Heavy chain 

• structure length (residues): 217

• mutations: No

• disulfide bridges: 22-96, 144-199

• CDR (residue numbering): 30-33, 50, 52-54, 56-58, 95-99

3.2 Light chain

• structure length (residues): 214

• mutations: No

• disulfide bridges: 23-88, 134-194 

• CDR (residue numbering): 31, 33, 92-95

RCSB PDB - 6BFS: GM-CSF in complex with human auto-antibody F1

6BFS, GM-CSF in complex with autoantibody F1 (310K, 37°C, 100 ns)  : random seed #1 RMSD, SASA, RMSF, Rg, H-bonds

6BFS, GM-CSF in complex with autoantibody F1 (311K, 38°C, 100 ns)  : random seed #1 RMSD, SASA, RMSF, Rg, H-bonds

6BFS, GM-CSF in complex with autoantibody F1 (312K, 39°C, 100 ns)  : random seed #1 RMSD, SASA, RMSF, Rg, H-bonds

6BFS, GM-CSF in complex with autoantibody F1 (313K, 40°C, 100 ns)  : random seed #1 RMSD, SASA, RMSF, Rg, H-bonds

6BFS, GM-CSF in complex with autoantibody F1 (310K, 37°C, 100 ns)  : random seed #2 RMSD, SASA, RMSF, Rg, H-bonds

6BFS, GM-CSF in complex with autoantibody F1 (311K, 38°C, 100 ns)  : random seed #2 RMSD, SASA, RMSF, Rg, H-bonds

6BFS, GM-CSF in complex with autoantibody F1 (312K, 39°C, 100 ns)  : random seed #2 RMSD, SASA, RMSF, Rg, H-bonds

6BFS, GM-CSF in complex with autoantibody F1 (313K, 40°C, 100 ns)  : random seed #2 RMSD, SASA, RMSF, Rg, H-bonds

6BFS, GM-CSF in complex with autoantibody F1 (310K, 37°C, 100 ns)  : random seed #3 RMSD, SASA, RMSF, Rg, H-bonds

6BFS, GM-CSF in complex with autoantibody F1 (311K, 38°C, 100 ns)  : random seed #3 RMSD, SASA, RMSF, Rg, H-bonds

6BFS, GM-CSF in complex with autoantibody F1 (312K, 39°C, 100 ns)  : random seed #3 RMSD, SASA, RMSF, Rg, H-bonds

6BFS, GM-CSF in complex with autoantibody F1 (313K, 40°C, 100 ns)  : random seed #3 RMSD, SASA, RMSF, Rg, H-bonds

GM-CSF  at 310K, 37°C, 100 ns: random seed #1  RMSD, SASA, RMSF, Rg, H-bonds

GM-CSF  at 311K, 38°C, 100 ns: random seed #1  RMSD, SASA, RMSF, Rg, H-bonds

GM-CSF  at 312K, 39°C, 100 ns: random seed #1 RMSD, SASA, RMSF, Rg, H-bonds

GM-CSF  at 313K, 40°C, 100 ns: random seed #1  RMSD, SASA, RMSF, Rg, H-bonds

GM-CSF  at 310K, 37°C, 100 ns: random seed #2 RMSD, SASA, RMSF, Rg, H-bonds

GM-CSF  at 311K, 38°C, 100 ns: random seed #2 RMSD, SASA, RMSF, Rg, H-bonds

GM-CSF  at 312K, 39°C, 100 ns: random seed #2 RMSD, SASA, RMSF, Rg, H-bonds

GM-CSF  at 313K, 40°C, 100 ns: random seed #2 RMSD, SASA, RMSF, Rg, H-bonds

GM-CSF  at 310K, 37°C, 500 ns: random seed #3 RMSD, SASA, RMSF, Rg, H-bonds

GM-CSF  at 311K, 38°C, 500 ns: random seed #3 RMSD, SASA, RMSF, Rg, H-bonds

GM-CSF  at 312K, 39°C, 500 ns: random seed #3 RMSD, SASA, RMSF, Rg, H-bonds

GM-CSF  at 313K, 40°C, 500 ns: random seed #3 RMSD, SASA, RMSF, Rg, H-bonds