1. Antibody: Durvalumab (Keytruda), an anti-PD-L1 antibody (engineered)

• Species: H. sapiens

• Isotype/subclass: IgG1k

• Structure: Fab only

3.1 Heavy chain 

• structure length (residues): 121

• mutations: No

• disulfide bridges: 22-96

• CDR (residue numbering): 34, 51, 53, 58, 60, 63, 100, 103, 104-106

3.2 Light chain

• structure length (residues): 114

• mutations: No

• disulfide bridges: 23-89

• CDR (residue numbering): 30, 31, 33, 92-95, 97

RCSB PDB: 5X8M - Crystal Structure of Durvalumab 

5X8M, anti-PD-L1 antibody, Durvalumab (298K, 25°C, 500 ns)       - random seed #1   >>    RMSD, SASA, RMSF, Rg.

5X8M, anti-PD-L1 antibody, Durvalumab (310K, 37°C, 500 ns)       - random seed #1   >>   RMSD, SASA, RMSF, Rg.

5X8M, anti-PD-L1 antibody, Durvalumab (311.5K, 38.5°C, 500 ns) - random seed #1   >>   RMSD, SASA, RMSF, Rg.

5X8M, anti-PD-L1 antibody, Durvalumab (313K, 40°C, 500 ns)       - random seed #1   >>   RMSD, SASA, RMSF, Rg.

5X8M, anti-PD-L1 antibody, Durvalumab (298K, 25°C, 500 ns)       - random seed #2   >>     RMSD, SASA, RMSF, Rg.

5X8M, anti-PD-L1 antibody, Durvalumab (310K, 37°C, 500 ns)       - random seed #2   >>   RMSD, SASA, RMSF, Rg.

5X8M, anti-PD-L1 antibody, Durvalumab (311.5K, 38.5°C, 500 ns) - random seed #2   >>    RMSD, SASA, RMSF, Rg.

5X8M, anti-PD-L1 antibody, Durvalumab (313K, 40°C, 500 ns)       - random seed #2  >>    RMSD, SASA, RMSF, Rg.