1. Complex: Der p 1 allergen in complex with Fab of mAb 10B9 

• CATH

• Resolution: 2.7 Å

• Species: Mus musculus, Dermatophagoides pteronyssinus 

2. Antigen:  Der p 1 from house dust mite (D. pteronyssinus )

• structure length (residues): 222

• mutations: No

• Uniprot

3. Antibody: mAb 10B9 

• Isotype/subclass: IgG1

• Structure: Fab only

3.1 Heavy chain 

• structure length (residues): 222

• mutations: No

• disulfide bridges: 22-95, 149-204

• CDR (residue numbering): 30, 56, 58, 100-103

3.2 Light chain

• structure length (residues): 211

• mutations: No

• disulfide bridges: 23-88, 134-194

• CDR (residue numbering): 32, 50, 91, 92

RCSB PDB - 5VCO: DER P 1 allergen in complex with Fab of mAb 10B9

DER P 1 allergen in complex with FAB fragment of MAB 10B9 (310K, 37°C, 100 ns) >> RMSD, SASA, RMSF, Rg, H-bonds

DER P 1 allergen in complex with FAB fragment of MAB 10B9 (311K, 38°C, 100 ns) >> RMSD, SASA, RMSF, Rg, H-bonds

DER P 1 allergen in complex with FAB fragment of MAB 10B9 (312K, 39°C, 100 ns) >> RMSD, SASA, RMSF, Rg, H-bonds

DER P 1 allergen in complex with FAB fragment of MAB 10B9 (313K, 40°C, 100 ns)   >> RMSD, SASA, RMSF, Rg, H-bonds