1. Complex: CD20 in complex with obinutuzumab 

• CATH

• Resolution: 1.6 Å

• Species: H. sapiens, Mus musculus

2. Antigen: peptide of B-lymphocyte antigen CD20, CD20

• structure length (residues): 25

• mutations: No

• Uniprot

3. Antibody: obinutuzumab (GA101), fully humanized

• Isotype/subclass: IgG1 (type II)

• Structure: Fab only

3.1 Heavy chain 

• structure length (residues): 224

• mutations: No

• disulfide bridges: 22-96, 146-202

• CDR (residue numbering): 33, 59, 79, 102-103

3.2 Light chain

• structure length (residues): 219

• mutations: No

• disulfide bridges: 23-93, 139-199

• CDR (residue numbering): 31, 37, 50, 96, 101.

RCSB PDB - 3PP4: Obinutuzumab in complex with CD20 

CD20 in complex with obinutuzumab (310K, 37°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

CD20 in complex with obinutuzumab (311K, 38°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

CD20 in complex with obinutuzumab (312K, 39°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

CD20 in complex with obinutuzumab (313K, 40°C, 100 ns) >> RMSD, SASA, RMSF, Rg, H-bonds