1. Complex: IL-16 in complex with 14.1 mAb 

• CATH

• Resolution: 2 Å

• Species: H. sapiens

2. Antigen: Interleukin-16, IL-16

• structure length (residues): 102

• mutations: No

• Uniprot

3. Antibody: 14.1 mAb 

• Isotype/subclass: IgG1

• Structure: Fab only

3.1 Heavy chain 

• structure length (residues): 224

• mutations: No

• CDR (residue numbering): 52, 74, 100-103, 109, 121, 122, 127

3.2 Light chain

• structure length (residues): 218

• mutations: No

• CDR (residue numbering): 59, 61, 78

 RCSB PDB - 5FB8: Structure of Interleukin-16 bound to the 14.1 antibody 

Interleukin-16 bound to mAb 14.1 (310K, 37°C, 200 ns) - random seed #1 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (311K, 38°C, 200 ns)  - random seed #1 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (312K, 39°C, 200 ns) - random seed #1 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (310K, 37°C, 200 ns) - random seed #2 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (311K, 38°C, 200 ns) - random seed #2 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (312K, 39°C, 200 ns) - random seed #2 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (310K, 37°C, 200 ns) - random seed #3 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (311K, 38°C, 200 ns) - random seed #3 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (312K, 39°C, 200 ns) - random seed #3 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (310K, 37°C, 200 ns) - random seed #4 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (311K, 38°C, 200 ns) - random seed #4 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (312K, 39°C, 200 ns) - random seed #4 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (310K, 37°C, 200 ns) - random seed #5 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (311K, 38°C, 200 ns) - random seed #5 >> RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-16 bound to mAb 14.1 (312K, 39°C, 200 ns) - random seed #5 >> RMSD, SASA, RMSF, Rg, H-bonds