1. Complex: IL-6 in complex with mAb 68F2 

• CATH

• Resolution: 2.9 Å

• Species: H. sapiens

2. Antigen: Interleukin-6, IL-6, IFN-beta-2 

• structure length (residues): 171

• mutations: No

• Uniprot

3. Antibody: 68F2 antibody

• Isotype/subclass: IgG1

• Structure: Fab only

3.1 Heavy chain 

• structure length (residues): 222

• mutations: No

• disulfide bridges: 22-97, 149-205

• CDR (residue numbering): 101-108

3.2 Light chain

• structure length (residues): 216

• mutations: No

• disulfide bridges: 22-90, 138-197

• CDR (residue numbering): 31-35

RCSB PDB - 4ZS7: IL-6 in complex with mAb 68F2 

Interleukin-6 (IL-6) in complex with antibody 68F2 (310K, 37°C, 100 ns) RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-6 (IL-6) in complex with antibody 68F2 (311K, 38°C, 100 ns) RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-6 (IL-6) in complex with antibody 68F2 (312K, 39°C, 100 ns) RMSD, SASA, RMSF, Rg, H-bonds

Interleukin-6 (IL-6) in complex with antibody 68F2 (313K, 40°C, 100 ns) RMSD, SASA, RMSF, Rg, H-bonds