1. Complex: CD40L in complex with 5C8 mAb 

• CATH

• Resolution: 3.1 Å

• Species: H. sapiens

2. Antigen: CD40 ligand, CD40L, CD154 

• structure length (residues): 146

• mutations: No

• Uniprot

3. Antibody: 5C8 (humanized)

• Isotype/subclass: IgG2a

• Structure: Fab + Fab + Fab

3.1 Heavy chain 

• structure length (residues): 219

• mutations: No

• disulfide bridges: 22-96, 145-201

• CDR (residue numbering): 31-33, 52, 54, 57, 59, 102, 103

3.2 Light chain

• structure length (residues): 218

• mutations: No

• disulfide bridges: 23-92, 138-198

• CDR (residue numbering): 31, 32, 36, 95, 96

RCSB PDB - 1I9R: CD40L in complex with 5C8 mAb 

CD40L in complex with 5C8 antibody (310K, 37°C, 100 ns)

CD40L in complex with 5C8 antibody (311K, 38°C, 100 ns)

CD40L in complex with 5C8 antibody (312K, 39°C, 100 ns)

CD40L in complex with 5C8 antibody (313K, 39°C, 100 ns)