1. Complex: CD27 in complex with a neutralizing noncompeting M2177 mAb 

• CATH

• Resolution: 1.8 Å

• Species: H. sapiens, Mus musculus.

2. Antigen: Cluster of Differentiation 27, CD27, TNFRSF7 

• structure length (residues): 109

• mutations: No

• Uniprot

3. Antibody: M2177 mAb 

• Isotype/subclass: IgG1

• Structure: Fab only

3.1 Heavy chain 

• structure length (residues): 229

• mutations: No

• disulfide bridges: 22-96, 147-203

• CDR (residue numbering): 33, 52, 55, 57, 102, 104, 105

3.2 Light chain

• structure length (residues): 218

• mutations: No

• disulfide bridges: 23-92, 138-198

• CDR (residue numbering): 31, 34, 36, 96

RCSB PDB - 5TL5: COMPLEX BETWEEN HUMAN CD27 AND ANTIBODY M2177 

CD27 in complex with M2177 antibody (310K, 37°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

CD27 in complex with M2177 antibody (311K, 38°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

CD27 in complex with M2177 antibody (312K, 39°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

CD27 in complex with M2177 antibody (313K, 40°C, 100 ns) >> RMSD, SASA, RMSF, Rg, H-bonds

RCSB PDB - 5TLJ: COMPLEX BETWEEN HUMAN CD27 AND ANTIBODY M2177 and M2191

CD27 in complex with M2177 antibody and M2191 (298K, 25°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

CD27 in complex with M2177 antibody and M2191 (310K, 37°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

CD27 in complex with M2177 antibody and M2191 (311K, 38°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

CD27 in complex with M2177 antibody and M2191 (312K, 39°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

CD27 in complex with M2177 antibody and M2191 (313K, 40°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds