1. Complex: COMP-epitope P6 in complex with 15A mAb 

• CATH

• Resolution: 1.9 Å

• Species: H. sapiens

2. Antigen: BP6 epitope of cartilage oligomeric matrix protein, COMP-epitope P6

• structure length (residues): 19

• mutations: No

• Uniprot

3. Antibody: 15A mAb 

• Isotype/subclass: IgG1

• Structure: Fab only.

3.1 Heavy chain 

• structure length (residues): 233

• mutations: No

• disulfide bridges: 22-96, 150-205

• CDR (residue numbering): 31, 33, 50, 52, 57, 59, 99, 108.

3.2 Light chain

• structure length (residues): 219

• mutations: No

• disulfide bridges: 23-93, 139-199

• CDR (residue numbering): 31, 96.

RCSB PDB - 6SF6: Crystal structure of the mAb 15A in complex with COMP-epitope P6

Crystal structure of mAb 15A with COMP-epitope P6 (310K, 37°C, 100 ns): random seed #1 >> RMSD, SASA, RMSF, Rg, H-bonds

Crystal structure of mAb 15A with COMP-epitope P6 (311K, 38°C, 100 ns): random seed #1 >> RMSD, SASA, RMSF, Rg, H-bonds

Crystal structure of mAb 15A with COMP-epitope P6 (312K, 39°C, 100 ns): random seed #1 >> RMSD, SASA, RMSF, Rg, H-bonds

Crystal structure of mAb 15A with COMP-epitope P6 (313K, 40°C, 100 ns): random seed #1 >> RMSD, SASA, RMSF, Rg, H-bonds

Crystal structure of mAb 15A with COMP-epitope P6 (310K, 37°C, 100 ns): random seed #2 >> RMSD, SASA, RMSF, Rg, H-bonds

Crystal structure of mAb 15A with COMP-epitope P6 (311K, 38°C, 100 ns): random seed #2 >> RMSD, SASA, RMSF, Rg, H-bonds

Crystal structure of mAb 15A with COMP-epitope P6 (312K, 39°C, 100 ns): random seed #2 >> RMSD, SASA, RMSF, Rg, H-bonds

Crystal structure of mAb 15A with COMP-epitope P6 (313K, 40°C, 100 ns): random seed #2 >> RMSD, SASA, RMSF, Rg, H-bonds

Crystal structure of mAb 15A with COMP-epitope P6 (310K, 37°C, 100 ns): random seed #3 >> RMSD, SASA, RMSF, Rg, H-bonds

Crystal structure of mAb 15A with COMP-epitope P6 (311K, 38°C, 100 ns): random seed #3 >> RMSD, SASA, RMSF, Rg, H-bonds

Crystal structure of mAb 15A with COMP-epitope P6 (312K, 39°C, 100 ns): random seed #3 >> RMSD, SASA, RMSF, Rg, H-bonds

Crystal structure of mAb 15A with COMP-epitope P6 (313K, 40°C, 100 ns): random seed #3 >> RMSD, SASA, RMSF, Rg, H-bonds

COMP-epitope P6 (310K, 37°C, 100 ns): random seed #1 >> RMSD, SASA, RMSF, Rg.

COMP-epitope P6 (311K, 38°C, 100 ns): random seed #1 >> RMSD, SASA, RMSF, Rg.

COMP-epitope P6 (312K, 39°C, 100 ns): random seed #1 >> RMSD, SASA, RMSF, Rg.

COMP-epitope P6 (313K, 40°C, 100 ns): random seed #1 >> RMSD, SASA, RMSF, Rg.

COMP-epitope P6 (310K, 37°C, 100 ns): random seed #2 >> RMSD, SASA, RMSF, Rg.

COMP-epitope P6 (311K, 38°C, 100 ns): random seed #2 >> RMSD, SASA, RMSF, Rg.

COMP-epitope P6 (312K, 39°C, 100 ns): random seed #2 >> RMSD, SASA, RMSF, Rg.

COMP-epitope P6 (313K, 40°C, 100 ns): random seed #2 >> RMSD, SASA, RMSF, Rg.