1. Complex: Clostridium dificile toxin B CROP domain in complex with Fab of bezlotoxumab 

• CATH

• Resolution: 2.8 Å

• Species: Clostridium dificile 

2. Antigen: Exotoxin B (TcdB) from Clostridium dificile 

• structure length (residues): 25

• mutations: No

• Uniprot

3. Antibody: bezlotoxumab  

• Isotype/subclass: IgG1

• Structure: Fab only

3.1 Heavy chain 

• structure length (residues): 222

• mutations: No

• disulfide bridges: 22-96, 146-202

• CDR (residue numbering): 33, 52, 54, 59, 100, 102, 104

3.2 Light chain

• structure length (residues): 215

• mutations: No

• disulfide bridges: 23-89, 135-195

• CDR (residue numbering): 33, 50, 95

RCSB PDB - 4NP4 - Clostridium dificile toxin B CROP domain in complex with Fab of bezlotoxumab 

C. dificile toxin B CROP domain in complex with bezlotoxumab (310K, 37°C, 100 ns)  >>  RMSD, SASA, RMSF, Rg, H-bonds

C. dificile toxin B CROP domain in complex with bezlotoxumab (311K, 38°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

C. dificile toxin B CROP domain in complex with bezlotoxumab (312K, 39°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds

C. dificile toxin B CROP domain in complex with bezlotoxumab (313K, 40°C, 100 ns) >>  RMSD, SASA, RMSF, Rg, H-bonds