1. Complex: Autoantibody CIIC1 in complex with triple-helical C1 peptide 

• CATH

• Resolution: 2.2 Å

• Species: H. sapiens

2. Antigen: Triple-helical C1 peptide containing the C1 epitope (GARGLTGROGDA; O = hydroxyproline) of Cartilage protein type II 

• structure length (residues): 34

• mutations: No

3. Antibody: Autoantibody CIIC1

• Class: IgG

• Structure: Fab only

3.1 Heavy chain 

• structure length (residues): 232

• mutations: No

• disulfide bridges: 22-96, 146-201

• CDR (residue numbering): 28, 31-33, 50, 52, 55-57, 59, 62, 63, 99, 101-104

3.2 Light chain

• structure length (residues): 218

• mutations: No

• disulfide bridges: 23-92, 138-198

• CDR (residue numbering): 27, 31, 32, 36. 54, 95-100

RCSB PDB - 2Y5T: Autoantibody CIIC1 in complex with the triple-helical C1 peptide 

Autoantibody CIIC1 in complex with a triple-helical C1 peptide (310K, 37°C, 100 ns) RMSD, SASA, RMSF, Rg, H-bonds

Autoantibody CIIC1 in complex with a triple-helical C1 peptide (311K, 38°C, 100 ns) RMSD, SASA, RMSF, Rg, H-bonds

Autoantibody CIIC1 in complex with a triple-helical C1 peptide (312K, 39°C, 100 ns) RMSD, SASA, RMSF, Rg, H-bonds

Autoantibody CIIC1 in complex with a triple-helical C1 peptide (313K, 40°C, 100 ns) RMSD, SASA, RMSF, Rg, H-bonds