1. Complex: CD22 d1-d3 in complex with Fab of Epratuzumab 

• CATH

• Resolution: 3.1 Å

• Species: H. sapiens

2. Antigen: Cluster of differentiation-22, CD22

• structure length (residues): 323

• mutations: 4

• Uniprot

3. Antibody: Epratuzumab 

• Isotype/subclass: IgG1

• Structure: Fab only

3.1 Heavy chain 

• structure length (residues): 222

• mutations: No

• disulfide bridges: 25-99, 146-202

• CDR (residue numbering): 27, 32, 33, 53, 58, 94-96, 102

3.2 Light chain

• structure length (residues): 222

• mutations: No

• disulfide bridges: 26-97, 142-202

• CDR (residue numbering): 27, 93

RCSB PDB - 5VL3: CD22 d1-d3 in complex with therapeutic Fab Epratuzumab 

CD-22 in complex with epratuzumab (310K, 37°C, 100 ns)

CD-22 in complex with epratuzumab (311K, 38°C, 100 ns)

CD-22 in complex with epratuzumab (312K, 39°C, 100 ns)

CD-22 in complex with epratuzumab (313K, 40°C, 100 ns)