LS1.1a - DNA Structure

LS1-1 Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.

Central Dogma of Biology DNA->RNA->Protein
- Form Dictates Function
- From Simple Instructions, complexity can arise
- Minor changes can have major impacts
- If something breaks, we know what it does.

DNA Extraction

Model 0: In Class Extraction

9. Banana DNA Lab

Model 1: From a Strawberry

DNA Extraction_How it Works

Strawberry DNA - Food Science | Experiments | Steve Spangler Science

All materials are easily purchased or you may already have them at home. The only exotic material is isopropyl alcohol (commonly referred to as rubbing alcohol). This can be purchased in small quantities at most pharmacies and larger grocery stores.

Model 2: From a BANANA

Model 3: From your CHEEK CELLS...

Model 4: Extract YOUR OWN DNA @ HOME!!!

If you want to get nerdy...

How To Extract DNA From Human Cheek CellsIt's easy to extract DNA from human cheek cells. You don't even need a lab. Here's how to do this experiment in your kitchen.

DNA EXTRACTION WORK

Journal, VLOG, record in some way your experience of extracting DNA in the classroom.
1. Create a whiteboard animation
2. Record a stop-motion animation
3. Create GIF of steps
4. Commercial to sell DNA extraction kit
5. Tutorial on how to extract the DNA of anything at home.
Submit a group copy to GC.

The Double Helix Model

From the shape of the individual molecules a complex structure can be formed. This structure then determines how the macromolecule functions.

Opt 1 - DNA Origami Model

DNA Paper Origami

DNA Origami - From Simple Instructions Complexity Arises

Version 1 - Written Instructions

Version 2 - Written Instructions

Opt 2 - 3D Printed Models

If you have a 3D printer at home and would like to print your model of DNA, here are some examples of the pre-made models available (if you find your a different model, print it...) If you want to create your own... OR CREATE some cool Jewelry

DNA Headphone Stand

DNA Pencil Holder

Interactive DNA Model

Folding DNA Model Kit

Opt 3 - A more Sophisticated Model

DNA Model Work:

Choose an option.
Build it.
Take a picture or video of it.
On your discuss the following idea:

From simple instructions, complexity arises.

Instructions to complete model - Written

Youtube Video Instructions:

You will need a minimum of Two of these sheets printed on heavy cardstock.

DNA Gizmo

Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created.

DNA GIZMO WORK

Complete the following:

Using the GIZMO - 3 steps.
DNA Vocabulary - Define and have a working knowledge of the terms listed.

Using the GIZMO

Build:
1. Following the directions on the GIZMO, create your own complete strand of DNA.
2. Describe the process you took to create the complete strand of DNA.
Photo:
1. Take a screenshot of your DNA Molecule.
2. Submit it on the Classroom assignment.
Practice:
1. Using the strand of DNA to the right.
2. Draw (create on GIZMO) the complete DNA molecule, submit a picture in your assignment.
Replicate:
1. Give a brief description of how a DNA molecule replicates (makes a copy of itself).
2. Mutations are very rare in the genetic code. Based on the process of DNA replication, explain why.

DNA Vocabulary - You will need to know these terms...

DNA
Double Helix
Enzyme
Mutation
Nitrogenous Base
Nucleotide
Replication

DNA Discovery

HHMI - The DNA Double Helix Discovery

KHAN Academy - Discovery of DNA

DNA as the genetic material | Biology library | Science | Khan AcademyThis unit is part of the Biology library. Browse videos, articles, and exercises by topic.

DNA Structure and Discovery

The Structure of DNAThis scrollable interactive takes users on a tour of the DNA double helix, explaining how nucleotide base pairing leads...

DNA Discovery Work

In any format of your choice,
1. Name 5 people or teams associated with the discovery of DNA's structure, for each person:
  1. describe the contributions they made to the discovery of DNA
  2. their background that led them to the contribution they made
  3. reasoning for why you chose these 5 people/teams (collectively or individually).

Watson and Crick

James D. Watson - Francis Crick, Books & Double HelixJames D. Watson is a Nobel Prize-winning biophysicist and researcher credited with co-discovering the double-helix structure of DNA.

Francis Crick - DNA, Education & James WatsonFrancis Crick is credited with co-discovering, along with James Watson, the double-helix structure of the DNA strand.

Rosalind Franklin's Contribution to the Discovery of DNA

Rosalind Franklin (1920-1958) was a British chemist and X-ray crystallographer who played a critical role in the discovery of the double helix structure of DNA1. Her work on X-ray diffraction images of DNA, particularly Photo 51, provided crucial evidence that led to this groundbreaking finding1.

Rosalind Franklin - DNA, Facts & DeathBritish chemist Rosalind Franklin is best known for her role in the discovery of the structure of DNA, and for her pioneering use of X-ray diffraction.

The Importance of Franklin's Work

Rosalind Franklin's work has had a profound impact on the advancement of science and medicine. Her X-ray diffraction studies of DNA laid the foundation for understanding DNA replication, recombination, and repair. This knowledge has been crucial for the development of new treatments for genetic diseases and for advancements in fields such as biotechnology and genetic engineering.

Nucleotide Pairing

DNA Fact Sheet.pdf

Based on your proposed nucleotides pairings, create a claim regarding the shape of the DNA molecule.
Strengthen your claim: Use the information in the DNA Fact Sheet to support or change your claim.
1. Cite specific evidence from the DNA Fact Sheet to support your claim.
Provide reasoning:
1. For each piece of evidence that you cite, provide the reason it supports your claim.

Nucleotides - A3

Page updated

Google Sites

Report abuse