Introduction
Although Comfey is usually known for its ability to snowball out of control with Calm Mind and Triage-boosted healing moves, this has not been the case in the January meta. This is mainly due to this set being completely walled by Unaware Clodsire, one of the highest usage mons. Comfey is by no means a bad Pokemon however, as players have discovered that it has arguably the best utility movepool in the entire metagame.
Utility
Comfey's movepool contains U-Turn, Defog, Knock Off, Toxic, Encore, and several other moves that grant it a unique jack-of-all-trades role that can be optimized to fit whatever your team needs. These sets typically run two of the above moves, an attacking move, and Synthesis for healing. For Comfey's attacking move, Draining Kiss with Triage is the most common option, as the priority helps against opposing Infernape. Another option is Alluring Voice with Natural Cure, which guarantees the OHKO against Crawdaunt and allows Comfey to recover from status. Comfey's EVs can be invested into physical defense, special defense, or a more mixed variant, depending on what you need it to answer. Unfortunately, however, even max physdef Comfey cannot safely switch into Crawdaunt, especially if it has Choice Band.
Calm Mind
As mentioned earlier, this set is usually useless if the opposing team has a Clodsire. However, if you can manage to weaken it throughout the game, Calm Mind Comfey can be a very threatening endgame cleaner, as not much else resists Draining Kiss. Stored Power is recommended for this set, as with a Life Orb boost it almost always 2HKOs Clodsire after 2 boosts. Rest with Chesto Berry is another option in case Comfey gets Toxic poisoned, though beware that Poison Jab Clodsire will win the 1v1 no matter what set you run.
Choice Specs
This set is largely unexplored, but Comfey's access to Trick allows it to potentially cripple Clodsire for the rest of the game. This makes it much easier for Comfey to sweep the rest of the team with Calm Mind. If your opponent doesn't have Clodsire for some reason, Specs Draining Kiss is difficult to switch into on its own.
Teammates
Comfey's utility sets can fit into virtually any team, but its Calm Mind sets require more support. Countermeasures to Clodsire, such as Reuniclus and Mesprit, are useful in this regard, the latter of which can also set Stealth Rocks. Slowbro is another common Clodsire answer that can slow pivot with Teleport and heal off any damage with Regenerator. Golurk can take advantage of Clodsire by forcing it to switch and dealing heavy damage with Choice Band boosted hits. If running Choice Specs with Trick, a Fairy-spam core with Alcremie could potentially work, though this would need a lot of support.
Written by Gcgoat