Urology MCQ

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ANTICOAGULATION: QUESTION: .

With regard to anticoagulation, which of the following statements is/are true? .

a. Warfarin (coumadin) inhibits the activity of vitamin K-dependent factors (II, VII, IX, and X)

b. Heparin enhances the effect of antithrombin on thrombin-mediated conversion of fibrinogen to fibrin

c. Theoretically, 1.28mg of protamine neutralizes 1 mg of heparin

d. The effects of vitamin K reversal take 48hr

e. An INR of more than 1.5 is considered safe for operation

answer