Пример 1
Key words: FtsZ, divisome дивисома, перегородка (септа septa ?)
Началось, как всегда, с растений. Читаю про пластиды и встречаю примечание, что в пластидах как и в бактериях роль тубулина играет белок FtsZ. Так как студенты и магистры в этом году сильно "тупят" на зачетном задании, решил сделать пример зачетного задания по белку FtsZ.
Ес-но, спрашиваю Scholar Google: FtsZ - всего 8780 статей, за 2010-2011 - 841 статья, и уже 30 статей за 2011 год!
Из этой тридцатки статей за 2011 год "взгляд упал" на Варвару Вентуру и Виктора Суржика из Гейдельберга. Вот их последняя статья:
Barbara Di Ventura & Victor Sourjik. Self-organized partitioning of dynamically localized proteins in bacterial cell division // Molecular Systems Biology 7 Article number: 457. doi:10.1038/msb.2010.111
http://www.nature.com/msb/journal/v7/n1/synopsis/msb2010111.html
Статья в свободном доступе, 9 мультиков в приложении.
http://www.nature.com/msb/journal/v7/n1/suppinfo/msb2010111_S1.html#msb2010111-s10
PubMed даёт (Di Venture B): Results: 5
1. Self-organized partitioning of dynamically localized proteins in bacterial cell division.
Di Ventura B, Sourjik V.
Mol Syst Biol. 2011 Jan 4;7:457.PMID: 21206490 [PubMed - in process] Free ArticleRelated citations
B Di Ventura… - Molecular Systems Biology, 2011 - nature.com
How cells manage to get equal distribution of their structures and molecules at cell division is
a crucial issue in biology. In principle, a feedback mechanism could always ensure equality by
measuring and correcting the distribution in the progeny. However, an elegant alternative ...
2 Reconstitution of Mdm2-dependent post-translational modifications of p53 in yeast.
Di Ventura B, Funaya C, Antony C, Knop M, Serrano L.
PLoS One. 2008 Jan 30;3(1):e1507.PMID: 18231594 [PubMed - indexed for MEDLINE] Free PMC ArticleFree textRelated citations
Scholar Google: [HTML] Reconstitution of Mdm2-dependent post-translational modifications of p53 in yeast
[HTML] from plos.orgB Di Ventura, C Funaya, C Antony, M Knop… - PloS one, 2008 - PLoS
Acting as a sensor of DNA damage, p53 dictates life or death depending on the ability of the
cell to cope with the damage and repair it. It is therefore subject to a tight regulation achieved
by a complex protein network [1]. p53, an evolutionarily conserved protein from worm to ...
Cited by 4 - Related articles - Cached - All 6 versions
Ander M, Beltrao P, Di Ventura B, Ferkinghoff-Borg J, Foglierini M, Kaplan A, Lemerle C, Tomás-Oliveira I, Serrano L.
Syst Biol (Stevenage). 2004 Jun;1(1):129-38.PMID: 17052123 [PubMed - indexed for MEDLINE] Related citations
[PDF] from dtu.dkM Ander, P Beltrao, B Di Ventura… - Syst. Biol, 2004 - server.elektro.dtu.dk
Abstract: SmartCell has been developed to be a general framework for modelling and simulation
of diffusion-reaction networks in a whole-cell context. It supports localisation and diffusion by
using a mesoscopic stochastic reaction model. The SmartCell package can handle any ...
Cited by 70 - Related articles - View as HTML - All 11 versions
4. From in vivo to in silico biology and back.
Di Ventura B, Lemerle C, Michalodimitrakis K, Serrano L.
Nature. 2006 Oct 5;443(7111):527-33. Review. PMID: 17024084 [PubMed - indexed for MEDLINE]Related citations
Scholar Google: From in vivo to in silico biology and back
B Di Ventura, C Lemerle, K Michalodimitrakis… - Nature, 2006 - nature.com
The massive acquisition of data in molecular and cellular biology has led to the renaissance
of an old topic: simulations of biological systems. Simulations, increasingly paired with
experiments, are being successfully and routinely used by computational biologists to ...
Cited by 115 - Related articles - BL Direct - All 10 versions
5. Space as the final frontier in stochastic simulations of biological systems.
Lemerle C, Di Ventura B, Serrano L.
FEBS Lett. 2005 Mar 21;579(8):1789-94. Review.PMID: 15763553 [PubMed - indexed for MEDLINE] Related citations
[PS] from inria.frA Alfonsi, E Cancès, G Turinici, B Di Ventura… - 2004 - hal.inria.fr
... Exact simulation of hybrid stochastic and deterministic models for biochemical systems
Aurщlien Alfonsi — Eric Cancшs — Gabriel Turinici — Barbara Di Ventura — Wilhelm
Huisinga NА 5435 December 2004 Page 2. Page 3. ...
Cited by 44 - Related articles - All 8 versions
Встретил новое слово divisome, связанное с FtsZ. Scholar Google даёт 580 статей, но быстрый просмотр первой сотни позволил увидеть редкую статью 1991 года и ссылку на неё, откуда следует, что само понятие divisome было введено в 1991 году.
[HTML] from nih.govF Van Den Ent… - The EMBO journal, 2000 - nature.com
... It is the first constitutional protein of the divisome, a hypothetical polyprotein complex
believed to carry out prokaryotic cell division (Nanninga, 1991). ... Before contraction, other
components of the divisome are sequentially recruited to the FtsZ ring. ...
Cited by 116 - Related articles - BL Direct - All 8 versions
Scholar Google: Cell division and peptidoglycan assembly in Eschenchia coli
N Nanninga - Molecular microbiology, 1991 - interscience.wiley.com
... It is suggested that a largely proteinaceous macromolecular complex (divisome) at the leading
edge of constriction encompasses three compart- ments (cytoplasm, membrane and periplasm). ...
Fig. 3. Peptidoglycan assembly at the leading edge (divisome) in nascent polar caps. ...
Cited by 108 - Related articles - All 5 versions
Запрос по ключевому слову «дивисома» даёт ссылку на обзор:
И. Е. Вишняков, С. Н. Борхсениус. Белок FtsZ и цитокинез у бактерий // Цитология, 2007. Том 49, No 5. c. 421-429.
Scholar Google: [PDF] БЕЛОК FtsZ И ЦИТОКИНЕЗ У БАКТЕРИЙ © И. Е. Вишняков, С. Н ...
Формат файлов: PDF/Adobe Acrobat - Быстрый просмотр
Аппарат деления бактериальной клетки (дивисома) на примере Escherichia coli. .... ния, входящих в состав дивисомы. Белки дивисомы и их ...
www.tsitologiya.cytspb.rssi.ru/49_5/vishnyakov.pdf - Похожие
Вот, пожалуй, и всё! Удалось сделать маленькое открытие в большой науке про цитоскелет всего-то за время одной ленты. Можно студентам эту страницу предложить в качестве примера. 15/1/11 18:18К