communicating with consultants and care team, and planning for disposition. 6. Demonstrate appropriate interpersonal communication skills in interactions with patients, family members, colleagues, and supervisors 7. Describe and/or demonstrate a basic approach to the following procedures when encountered in clinical practice: ABG, IV placement, Central line placement, Lumbar puncture, Endotracheal intubation Nasogastric tube placement, CPR, Decompression of pneumothorax, Pericardiocentesis, Laceration repair, Medical resuscitation, Trauma resuscitation. 8. Participate as a member of the critical care resuscitation team for seriously ill and injured patients. ACCM: During the Anesthesiology clerkship, students work directly with a senior anesthesia resident in ORs and procedural suites throughout the hospital to provide general anesthesia and monitored anesthesia care to a wide variety of patients. Students are active participants in patient care and will perform important life-saving skills including: face mask ventilation, intravenous catheter placement, airway device insertion and management (laryngeal mask airway placement endotracheal intubation), IV medication administration, interpretation of vital signs, hemodynamic changes, and imaging studies. Students may perform or assist with advanced skills such as fiberoptic intubations, arterial line placement central line placement, epidural catheter placement, and ultrasound guided procedures. The skills acquired during the clerkship in anesthesiology are broadly applicable to a wide variety of fields and are particularly useful in rapid response and code situations. Students are active participants in comprehensive perioperative care from conducting the preoperative evaluation prior to induction, to performing procedures and management during and after induction, to signing out to the PACU/ICU team postoperatively. Students receive one-on-one teaching in the operating room from anesthesia residents and attendings who are engaged, active teachers and who view students as integral members of the team. Students learn about physiology and pharmacology in real-time by administering medications and other interventions and observing the changes in hemodynamics. Students are assigned with the overnight call team to give them exposure to emergency cases, traumas, codes, and other types of cases may not occur during the day. Simulation sessions and didactics augment the intraoperative learning experience during the rotation. A case discussion session at the conclusion of the clerkship will include a discussion of fundamental anesthesia concepts and presentation of a medically challenging 18 ANESTHESIOLOGY AND CRITICAL CARE MEDICINE clinical case. Many students have gone on to present their clinical cases at national and international scientific meetings. Objectives are cumulative and students will continue to practice and build on clinical skills as the clerkship progresses. By the end of Week 1, students will: 1. Perform a comprehensive airway anatomy exam prior to induction of anesthesia 2. Assist in the pre-operative OR preparation, including IV set up, airway equipment, medications, and anesthesiology machine and monitor check 3. Perform mask ventilation skills including insertion of airway adjunct devices 4. Learn direct laryngoscopy and LMA placement techniques 5. Learn peripheral IV placement techniques with and without ultrasound guidance 6. Classify patient’s health status and medical co-morbidities based on ASA status 7. Understand and research the pharmacology of different medications used for induction, maintenance, and emergence from anesthesia. 8. Perform focused pre-anesthesia assessments and physical exams 9. Attempt arterial line placement and other advanced techniques 10. Interpret intra-operative monitors 11. Develop a perioperative plan for patient management By the end of week 2, students will: 1. Name criteria for extubation, both clinical and subjective considerations 2. Explain the concept of MAC, particularly how it varies in different patients 3. Identify co-morbidities that may affect anesthetic management 4. Discuss the components of the ASA difficult airway algorithm 5. Perform advanced airway techniques, such as video laryngoscopy 6. Show proficiency and independence in mask ventilation and IV insertion techniques 7. Provide detailed clinical sign out or handoff reports to PACU/ICU teams 8. Independently prepare an OR for the start of a case (including medications, airway equipment, suctioning, IV tubing, etc.) 9. Interpret hemodynamic changes and provide interventions during intraoperative management 19 BIOLOGICAL CHEMISTRY BIOLOGICAL CHEMISTRY RESEARCH OPPORTUNITIES IN THE DEPARTMENT OF BIOLOGICAL CHEMISTRY DR. MICHAEL CATERINA Molecular and physiological mechanisms responsible for pain sensation. DR. ROBERT COLE Understanding the role of proteins, their modifications, adductomes and interactomes in human health and disease through innovative proteomics. DR. RYUYA FUKUNAGA Biology and mechanism of post-transcriptional gene regulation by small silencing RNAs and RNA-binding proteins. DR. ERIN GOLEY Bacterial cell biology: growth and adaptation mechanisms of bacteria in different environments. DR. STEVE GOULD HIV/AIDS; retrovirology;