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RELEVANT LEARNING OUTCOME:
(b) Describe how the genomes of viruses are inherited through outlining the reproductive cycles of
iii. retroviruses, e.g. HIV.
🕐Estimated time for this section: 25 minutes
HIV Reproductive Cycle
HIV Reproductive Cycle
👁️🗨️ Watch the video, 0:00- 4:56 to learn about the reproductive cycle of HIV.
Think about these questions:
How is the virus taken into the host cell?
How does the viral genome gets replicated?
What is viral maturation?
🖊️Check Your Understanding: Lecture notes Concept Check 3
🖊️Check Your Understanding: Lecture notes Concept Check 3
1. Describe how HIV acquires the outer envelope – how does new virion acquire their viral envelope (include viral glycoproteins). [3 marks]
HIV is released from an infected cell through budding.
During the process, the cell surface membrane of the host cell becomes the outer envelope of the virus that surrounds viral RNA and proteins.
Prior to budding, viral glycoproteins (e.g., transmembrane glycoprotein gp41 and surface glycoprotein gp120) are synthesised, transported to the host cell surface where they are embedded within the cell surface membrane of the host cell.
During the budding of the virus from the host cell, the glycoproteins become part of the outer envelope of the new HIV.
🖊️Check Your Understanding: Learning Goals
🖊️Check Your Understanding: Learning Goals
Attempt Qn 5 to 11 of Animal Virus Learning Goals
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