RELEVANT LEARNING OUTCOME:
(a) Discuss the bioethics of genetic material screening for mutations, including trisomy-21.
Complete this SLS lesson to gain an understanding of bioethics.
Through the SLS lesson, you should have learnt what is bioethics, and the four guiding principles used in guiding one to make a decision.
You may watch the video for a quick recap on the 4 guiding principles:
Autonomy
Beneficence
Non-maleficence
Justice
As you watch the video, remember that there is no right or wrong decision to a bioethical dilemma, but rather, how you use the principle to justify your decision.
One key difference to note regarding genetic screening compared to genetic testing is that:
genetic screening identifies the risk of the disease (e.g., high/low risk) - it does not indicate if the patient have or not have the disease.
genetic testing diagnose the patient to confirm if the patient have or do not have the disease
It is also important to note that for any screening or tests, there are chances of false positives:
False positive in genetic screening:
individuals who actually do not have the disease but screened as high risk
False positives in genetic testing:
individuals who actually do not have the disease but tested positive for the disease.
This comes about from the limitation of any genetic screening or tests, it cannot be 100% specific and sensitivity.
👁️watch the video to learn more about the 4 possible outcomes from any screening/tests.
With your understanding of bioethics, the 4 guiding principles, along with genetic screening and tests, complete this SLS lesson to:
identify the ethical dilemma in genetic maternal screening for Down's syndrome
gain an understanding of the different view points of various stakeholders regarding the ethical dilemma
using the claim-evidence-reasoning (CER) framework, construct a justification for a chosen decision for the ethical dilemma
Check your understanding by attempting Qn 29 - 38 of the DNA Mutations Learning Goals.