Skills 2-4

History and structure of DNA

Skill 2:  What are the major contributions of Erwin Chargaff, Rosalind Franklin, James Watson, Francis Crick, and Friedrich Miescher?

Rosalind Franklin took x-rays (radiografía) of DNA to find the shape.

There are four nitrogen bases in DNA, A, T, C, and G.  Erwin Chargaff discovered that 'A' pairs with 'T' and 'C' pairs with 'G.'  Remember, "When I hike the appalachian trail, I take a cute guy/girl."

James Watson and Francis Crick won the Nobel Prize for discovering that DNA has a double helix shape, which is like a twisted ladder (escalera retorcida).  Someone shared Franklin's work with them, which they combined with their own work to finally pin down the shape of DNA.

(Miescher will be found in the Crash Course video below.)

Click here to access the Crash Course Video on DNA replication.  Answer the questions in your packet.

Click here to access the Amoeba Sisters video comparing and contrasting DNA and RNA.

Complete the chart in your packet,  listing the three main differences between DNA and RNA.

Skill 3: Explain the shape of DNA and tell how nitrogen bases pair up.

Skill 4: Explain the purpose of DNA replication and describe the process.

At the beginning of day 2, I will have a class discussion to explain DNA replication.  If you get here before that or you are absent that day, watch the video below and fill out the DNA replication page on your own in pencil then move on to skill 5.